Evidence map›Paper›PMID 35816916›Full record

Trial reportBehaviour research and therapy2022

Effects of personalized depression prevention on anxiety through 18-month follow-up: A randomized controlled trial.

Jason D Jones, Benjamin L Hankin, Robert Gallop, Dustin Haraden, Marissa D Sbrilli, Judy Garber, Jami F Young

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Behaviour research and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Personalized Depression Prevention Reduces Dependent Stressors Among Adolescents: Results from a Randomized Controlled Trial.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Trial
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jason D JonesChildren's Hospital of Philadelphia, United States; University of Pennsylvania Perelman School of Medicine, United States. Electronic address: jonesjd@chop.edu.
Benjamin L HankinUniversity of Illinois, Urbana-Champaign, United States.
Robert GallopWest Chester University, United States.
Dustin HaradenUniversity of Illinois, Urbana-Champaign, United States.
Marissa D SbrilliUniversity of Illinois, Urbana-Champaign, United States.
Judy GarberVanderbilt University, United States.
Jami F YoungChildren's Hospital of Philadelphia, United States; University of Pennsylvania Perelman School of Medicine, United States.
University of Illinois Urbana-Champaign · USChildren's Hospital of Philadelphia · USVanderbilt University · USWest Chester University · US

Funding

Genetic cognitive and interpersonal vulnerabilities to depression in youthR01MH077178 · NIMH · RUTGERS, THE STATE UNIV OF N.J. · PI YOUNG, JAMI F · 2007 to 2017
$3.6M
Genetic cognitive and interpersonal vulnerabilities to depression in youthR01MH077195 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HANKIN, BENJAMIN L · 2007 to 2017
$3.4M
NIMH NIH HHS R01 MH077178NIMH NIH HHS R01 MH077195
6 · The paper itself

Abstract

Depression and anxiety frequently co-occur and share several risk factors. There is some evidence for transdiagnostic effects of prevention programs on depression and anxiety. In the Personalized Depression Prevention (PDP) study, youth (n = 98, Mage = 13.94 years, SD = 1.67) were classified as high or low on cognitive and interpersonal risk factors and randomized to either a cognitive-behavioral or an interpersonal prevention program. Some participants received a match between risk and prevention, others received a mismatch. Our initial work found evidence for the benefits of personalization on depression outcomes. In this paper, we focus on secondary anxiety outcomes through 18-months post-intervention. We found evidence for the benefits of personalized prevention on anxiety symptoms during the 18-month follow-up period, but not during the intervention. From post-intervention to 18-month follow-up matched youth showed a decrease in anxiety symptoms whereas mismatched youth showed a significant increase in symptoms (d = 0.87, p = .001). The rates of anxiety disorders were equivalent across the groups (p = 1.00). Given the comorbidity of depression and anxiety, interventions that have effects on both may be an efficient and cost-effective approach to reducing the burden associated with these conditions. A risk-informed personalization approach to prevention may be one way to enhance the transdiagnostic effects of depression prevention.

Indexed as

AnxietyDepressionAdolescentAnxiety DisordersComorbidityCost-Benefit AnalysisHumansAdolescentsAnxietyDepressionPersonalizationPreventionTransdiagnostic

Identifiers

PMID35816916
PMCPMC12906896
OpenAlexW4283798196

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.