Evidence map›Paper›PMID 35816791›Full record

ArticleThe International journal on drug policy2022

Drug use behaviors, trauma, and emotional affect following the overdose of a social network member: A qualitative investigation.

Alexandria Macmadu, Lisa Frueh, Alexandra B Collins, Roxxanne Newman, Nancy P Barnett, Josiah D Rich, Melissa A Clark, Brandon D L Marshall

Open access · greenAbstract read
In one paragraph

Article in The International journal on drug policy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Alexandria MacmaduDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA.
Lisa FruehHarvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA.
Alexandra B CollinsDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA.
Roxxanne NewmanDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA.
Nancy P BarnettDepartment of Behavioral and Social Sciences, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA.
Josiah D RichThe Center for Health + Justice Transformation, The Miriam Hospital, 1125 North Main Street, Providence, RI, USA.
Melissa A ClarkDepartment of Health Services, Policy & Practice, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA.
Brandon D L MarshallDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA. Electronic address: brandon_marshall@brown.edu.
Brown University · USHarvard University · USMiriam Hospital · US

Funding

Project 4: Neonatal Abstinence Syndrome (NAS): Fetus to First YearsP20GM125507 · NIGMS · RHODE ISLAND HOSPITAL · PI Ju Nyeong Park · 2018 to 2026
$23.4M
The Rhode Island Young Adult Prescription and Illicit Drug Study (RAPIDS): Responding to Fentanyl and Associated HarmsR01DA047975 · NIDA · BROWN UNIVERSITY · PI MARSHALL, BRANDON DAVID LEWIS · 2019 to 2023
$3.8M
Examining the impact of nonfatal and fatal overdose in social networks on individual overdose riskF31DA052971 · NIDA · BROWN UNIVERSITY · PI MACMADU, ALEXANDRIA · 2021 to 2022
$71k
NIDA NIH HHS F31 DA052971NIDA NIH HHS R01 DA047975NIGMS NIH HHS P20 GM125507
6 · The paper itself

Abstract

backgroundScant research has examined the influence of overdoses occurring in social networks (i.e., knowing someone who has overdosed) on individual overdose risk. We sought to characterize drug use behaviors of individuals following the overdose of someone in their social network.

methodsWe conducted semi-structured interviews with 25 people who use drugs and knew someone who overdosed in the prior 90 days. All interviews were conducted in person in Rhode Island from July to October 2021. Data were stratified by drug use behaviors following the overdose of a network member (i.e., risk behaviors, protective behaviors, no change; selected a priori) and analyzed using a thematic analysis variation to identify salient themes.

resultsWe identified variation in the effect of knowing someone who overdosed on subsequent drug use behaviors and emotional affect. Several participants described increasing their drug use or using more types of drugs than usual to manage feelings of bereavement and trauma, and a subset of these participants described increased drug use with suicidal intention and increased suicidal ideations following the overdose event. Other participants described reducing their drug use and engaging in protective behaviors in response to heightened perceived overdose risk, protection motivation (i.e., increased motivation to protect oneself), and concern for others. Additionally, some participants reported no change in drug use behaviors, and these participants described already engaging in harm reduction practices, feeling desensitized due to frequent or repeated exposure to overdose, and ambivalence about living.

conclusionsFindings suggest a need for enhanced investment in network-based overdose prevention interventions, as well as more robust integration of bereavement support and mental health services in settings that serve people who use drugs. The findings also suggest a need for future research to identify mediators of the effect of overdose occurring in social networks on individual overdose risk.

Indexed as

Drug OverdoseSubstance-Related DisordersAnalgesics, OpioidHarm ReductionHumansRisk-TakingSocial NetworkingAnalgesics, OpioidDrug use behaviorsOverdoseSocial influenceSocial networks

Identifiers

PMID35816791
PMCPMC9462427
OpenAlexW4284971264

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.