SynthesisJournal of medical Internet research2022
Misinformation About COVID-19 Vaccines on Social Media: Rapid Review.
Synthesis in Journal of medical Internet research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
148 citing papers in PubMed, 6 syntheses or guidelines pooled it, 315 citations in OpenAlex.
- Media Exposure and Its Association With Vaccine Attitudes, Intentions, and Hesitancy: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Social Media as an Effective Provider of Quality-Assured and Accurate Information to Increase Vaccine Rates: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Approaches to Research Ethics in Health Research on YouTube: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Psychological Inoculation for Credibility Assessment, Sharing Intention, and Discernment of Misinformation: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2023Pooled it
- Interventions for COVID-19 Vaccine Hesitancy: A Systematic Review and Narrative Synthesis.International journal of environmental research and public health · 2023Pooled it
- The Prevalence, Features, Influencing Factors, and Solutions for COVID-19 Vaccine Misinformation: Systematic Review.JMIR public health and surveillance · 2023Pooled it
- Codesigning COVID-19 booster promotion materials in online workshops with long-term care staff: a process evaluation.Health education research · 2026Trial
- Greater Improvements in Vaccination Outcomes Among Black Young Adults With Vaccine-Resistant Attitudes in the United States South Following a Digital Health Intervention: Latent Profile Analysis of a Randomized Control Trial.JMIR public health and surveillance · 2025Trial
- The Resilience of Attitude Toward Vaccination: Web-Based Randomized Controlled Trial on the Processing of Misinformation.JMIR formative research · 2024Trial
- Misinformation Through the Lens of Dutch News Media and Public Health Authorities: Content Analysis of Topics and Narratives Present in Pandemic-Related Misinformation During COVID-19.JMIR infodemiology · 2026Article
- Perspectives on COVID-19 vaccine decision-making in women of reproductive age: A social approach.Patient education and counseling · 2026Article
- Review
- Trust in government, public health authorities, health scientists and medical care providers and COVID-19 vaccines among Canadian adults.Scientific reports · 2026Article
- Understanding HIV Vaccine Misinformation and Vaccine Intentions Among Young Women in South Africa: Insights from an Online Survey.AIDS and behavior · 2026Article
- Mpox Vaccine Hesitancy Among Sexually Active People with HIV in Care at Risk for mpox.AIDS and behavior · 2026Article
- A coupled disease-misinformation model of measles transmission in the Canadian context.Infectious Disease Modelling · 2026Article
- "I didn't believe it was real": a qualitative exploration of COVID-19 vaccine hesitancy among key populations living with HIV/AIDS in Rivers State, Nigeria.BMC public health · 2026Article
- The role of institutional trust in shaping the relationship between vaccine concerns and ongoing COVID-19 vaccination in a US national cohort.American journal of epidemiology · 2026Article
- Understanding Vaccine Hesitancy in Louisiana Through Social Media Listening and Community Feedback: Cross-Sectional Study.JMIR infodemiology · 2026Article
- Review
88 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe development of COVID-19 vaccines has been crucial in fighting the pandemic. However, misinformation about the COVID-19 pandemic and vaccines is spread on social media platforms at a rate that has made the World Health Organization coin the phrase infodemic. False claims about adverse vaccine side effects, such as vaccines being the cause of autism, were already considered a threat to global health before the outbreak of COVID-19.
objectiveWe aimed to synthesize the existing research on misinformation about COVID-19 vaccines spread on social media platforms and its effects. The secondary aim was to gain insight and gather knowledge about whether misinformation about autism and COVID-19 vaccines is being spread on social media platforms.
methodsWe performed a literature search on September 9, 2021, and searched PubMed, PsycINFO, ERIC, EMBASE, Cochrane Library, and the Cochrane COVID-19 Study Register. We included publications in peer-reviewed journals that fulfilled the following criteria: original empirical studies, studies that assessed social media and misinformation, and studies about COVID-19 vaccines. Thematic analysis was used to identify the patterns (themes) of misinformation. Narrative qualitative synthesis was undertaken with the guidance of the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 Statement and the Synthesis Without Meta-analysis reporting guideline. The risk of bias was assessed using the Joanna Briggs Institute Critical Appraisal tool. Ratings of the certainty of evidence were based on recommendations from the Grading of Recommendations Assessment, Development and Evaluation Working Group.
resultsThe search yielded 757 records, with 45 articles selected for this review. We identified 3 main themes of misinformation: medical misinformation, vaccine development, and conspiracies. Twitter was the most studied social media platform, followed by Facebook, YouTube, and Instagram. A vast majority of studies were from industrialized Western countries. We identified 19 studies in which the effect of social media misinformation on vaccine hesitancy was measured or discussed. These studies implied that the misinformation spread on social media had a negative effect on vaccine hesitancy and uptake. Only 1 study contained misinformation about autism as a side effect of COVID-19 vaccines.
conclusionsTo prevent these misconceptions from taking hold, health authorities should openly address and discuss these false claims with both cultural and religious awareness in mind. Our review showed that there is a need to examine the effect of social media misinformation on vaccine hesitancy with a more robust experimental design. Furthermore, this review also demonstrated that more studies are needed from the Global South and on social media platforms other than the major platforms such as Twitter and Facebook.
trial registrationPROSPERO International Prospective Register of Systematic Reviews CRD42021277524; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021277524. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.31219/osf.io/tyevj.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.