Evidence map›Paper›PMID 35816641›Full record

ReviewAmerican journal of physiology. Cell physiology2022

Emerging mechanisms of elastin transcriptional regulation.

Sara S Procknow, Beth A Kozel

Open access · greenAbstract readReview
In one paragraph

Review in American journal of physiology. Cell physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  4. Article
  5. Review
  6. Review
  7. Article
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  9. Article
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  12. Article
  13. RiboScreenInternational journal of molecular sciences · 2024
    Article
  14. Pulmonary fibroelastosis - A review.Matrix biology : journal of the International Society for Matrix Biology · 2023
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sara S ProcknowDepartment of Pediatrics, Washington University School of Medicine, St. Louis, Missouri.ORCID 0000-0002-3023-6482
Beth A KozelTranslational Vascular Medicine Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.ORCID 0000-0002-9757-7118
National Institutes of Health · USWashington University in St. Louis · US

Funding

Pediatric Cardiovascular and Pulmonary Research Training Program.T32HL125241 · NHLBI · WASHINGTON UNIVERSITY · PI Juliane Bubeck Wardenburg, Kory J. Lavine · 2015 to 2026
$4.1M
Connective Tissue Mediated Vascular DiseaseZIAHL006244 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KOZEL, BETH · 2019 to 2024
$3.9M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL006212NHLBI NIH HHS T32 HL125241
6 · The paper itself

Abstract

Elastin provides recoil to tissues that stretch such as the lung, blood vessels, and skin. It is deposited in a brief window starting in the prenatal period and extending to adolescence in vertebrates, and then slowly turns over. Elastin insufficiency is seen in conditions such as Williams-Beuren syndrome and elastin-related supravalvar aortic stenosis, which are associated with a range of vascular and connective tissue manifestations. Regulation of the elastin (

Indexed as

Aortic Stenosis, SupravalvularMicroRNAsWilliams SyndromeAnimalsElastinGene Expression RegulationHumansElastinMicroRNAselastinpromotersupravalvar aortic stenosistranscriptionWilliams syndrome

Identifiers

PMID35816641
PMCPMC9448287
OpenAlexW4285012039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.