ArticleAmerican journal of respiratory and critical care medicine2022
Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease.
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Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
10.6field-weighted citation impact, top 1% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Clinical effects of N-acetylcysteine in ICU patients with respiratory disease: a systematic review and meta-analysis.Respiratory research & clinical practice · 2026Pooled it
- Saline nasal irrigation and gargling in COVID-19: Part II. Outcomes in Omicron and risk-benefit for self-care.Frontiers in public health · 2025Pooled it
- Mucins and Respiratory Virus Infection.Annual review of virology · 2026Review
- SARS-CoV-2 infection produces an IL-33-dependent chronic eosinophilic pneumonia and muco-inflammatory airways disease in Scnn1b-Tg mice.JCI insight · 2026Article
- Efficient replication of influenza D virus in the human airway underscores zoonotic potential.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Efficient replication of influenza D virus in the human airway underscores zoonotic potential.bioRxiv : the preprint server for biology · 2026Article
- Maintenance and disruption of mucous barrier homeostasis: the critical role of MUC5AC/MUC5B balance in airway diseases.Frontiers in medicine · 2026Review
- MicroRNA mapping of bronchial aspirate for molecular phenotyping and prognostication in patients on mechanical ventilation.Molecular therapy. Nucleic acids · 2025Article
- The Safety of Nebulized Conjugated Linoleic Acid for COVID-19 Respiratory Tract Infections.Cureus · 2025Article
- Development of an inhalable dry powder formulation for inhibition of SARS-CoV-2.International journal of pharmaceutics: X · 2025Article
- SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation.Nature microbiology · 2025Article
- Airway epithelial SARS-CoV-2 infectious and repair responses: relationships to age, sex, and post-COVID pulmonary syndromes.bioRxiv : the preprint server for biology · 2025Article
- Saliva Has High Sensitivity and Specificity for Detecting SARS-CoV-2 Compared to Nasal Swabs but Exhibits Different Viral Dynamics from Days of Symptom Onset.Diagnostics (Basel, Switzerland) · 2025Article
- Airway Basal Stem Cells Inflammatory Alterations in COVID-19 and Mitigation by Mesenchymal Stem Cells.Cell proliferation · 2025Article
- Prolonged airway explant culture enables study of health, disease, and viral pathogenesis.Science advances · 2025Article
- IL-33 is associated with alveolar dysfunction in patients with viral lower respiratory tract disease.Mucosal immunology · 2025Article
- The prevalence and influencing factors of COVID-19 in pregnant women post-relaxation of epidemic control measures in Hunan Province, China.Frontiers in medicine · 2025Article
- Fu Tu Sheng Jin Rehabilitation Formula Mitigate Airway Inflammation, Mucus Secretion and Immune Dysfunction Induced by SARS-CoV-2 Spike Protein.Journal of inflammation research · 2025Article
- PROS1 released by lung basal cells limits inflammation in epithelial and monocytes during SARS-CoV-2 infection.Discovery immunology · 2025Article
- Live imaging of airway epithelium reveals that mucociliary clearance modulates SARS-CoV-2 spread.Nature communications · 2024Article
Corrections and comments
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Authors and funding
25 authors at 6 institutions in 2 countries.
Takafumi KatoMarsico Lung Institute.ORCID 0000-0003-2248-3376
Takanori AsakuraMarsico Lung Institute.ORCID 0000-0003-3122-6937
Caitlin E EdwardsDepartment of Epidemiology.
Hong DangMarsico Lung Institute.
Yu MikamiMarsico Lung Institute.
Kenichi OkudaMarsico Lung Institute.ORCID 0000-0001-9341-2730
Gang ChenMarsico Lung Institute.
Ling SunMarsico Lung Institute.
Rodney C GilmoreMarsico Lung Institute.
Padraig HawkinsMarsico Lung Institute.
Gabriela De la CruzPathology Services Core, Lineberger Comprehensive Cancer Center, and.
Michelle R CooleyDepartment of Epidemiology.
Alexis B BaileyDepartment of Epidemiology.
Stephen M HewittLaboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Daniel S ChertowCritical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, Maryland; and.
Alain C BorczukDepartment of Pathology and Laboratory Medicine and.
Steven SalvatoreDepartment of Pathology and Laboratory Medicine and.
Fernando J MartinezPulmonary Critical Care Medicine, Weill Cornell Medicine, New York, New York.
Leigh B ThorneDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Frederic B AskinDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Camille EhreMarsico Lung Institute.
Scott H RandellMarsico Lung Institute.
Wanda K O'NealMarsico Lung Institute.
Ralph S BaricDepartment of Epidemiology.
Richard C BoucherMarsico Lung Institute.
Lung Institute · USUniversity of North Carolina at Chapel Hill · USCornell University · USNational Institutes of Health · USNational Institutes of Health Clinical Center · USSegeberger Kliniken · DE
Funding
PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT S. SANDLER · 1985 to 2026
$30.5MVector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Scott H Randell · 2004 to 2026
$26.5MThe Biophysics of Mucus Hydration and Adhesion/CohesionP01HL108808 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2012 to 2021
$23.9MExperimental Pathology Laboratory (EPL)ZICBC011638 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HEWITT, STEPHEN · 2015 to 2025
$16.6MDeterminants of Coronavirus Fidelity in Replication and PathogenesisR01AI108197 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BARIC, RALPH S, DENISON, MARK R · 2013 to 2022
$6.5MSynthesis of Effective and Safe Mucolytics for Pulmonary DiseaseUH3HL123645 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2016 to 2018
$4.6MGenetic Analysis of COVID-19 Susceptibility and Resistance Determinants in the Collaborative CrossR01AI157253 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BARIC, RALPH S, HEISE, MARK T · 2020 to 2024
$3.8MMultiscale Biochemical/Biophysical Integration of Pulmonary Mucus TransportR01HL136961 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2017 to 2020
$3.2MThe molecular and cellular mechanisms of the STAT3 mutation-mediated pulmonary disorder in Autosomal Dominant Hyper IgE Syndrome (AD-HIES)U01HL156655 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES, CHEN, GANG · 2022 to 2025
$3.0MRole of the ER stress transcription factor XBP1S in the development of idiopathic pulmonary fibrosisR01HL155951 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHEN, GANG · 2021 to 2025
$2.0MClinical and Molecular Features of Coronavirus Disease 2019ZIACL090070 · CLC · CLINICAL CENTER · PI CHERTOW, DANIEL S · 2020 to 2025
$0kNHLBI NIH HHS P01 HL108808NHLBI NIH HHS R01 HL136961NHLBI NIH HHS R01 HL155951NHLBI NIH HHS U01 HL156655NHLBI NIH HHS UH3 HL123645NIAID NIH HHS R01 AI108197NIAID NIH HHS R01 AI157253NIDDK NIH HHS P30 DK034987NIDDK NIH HHS P30 DK065988NIH HHS P01 HL108808NIH HHS P30 DK 034987NIH HHS P30 DK 065988NIH HHS R01 HL136961NIH HHS R01 HL155951NIH HHS UH3 HL123645
Abstract
PubMed holds no abstract for this paper.
Indexed as
COVID-19ErbB ReceptorsHumansLungMucin 5ACMucin-5BMucusPrevalenceRNASARS-CoV-2ErbB ReceptorsMucin 5ACMucin-5BRNAairway mucinCOVID-19MUC5ACMUC5BSARS-CoV-2
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.