Evidence map›Paper›PMID 35816339›Full record

ArticleACS chemical biology2022

A High-Throughput Fluorescent Turn-On Assay for Inhibitors of DHHC Family Proteins.

Tian Qiu, Saara-Anne Azizi, Noah Brookes, Tong Lan, Bryan C Dickinson

Open access · hybridAbstract read
In one paragraph

Article in ACS chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Recent Overview of Protein Palmitoylation and Profiling Methodologies.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  5. Mechanisms and functions of protein S-acylation.Nature reviews. Molecular cell biology · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tian QiuDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0002-7168-0715
Saara-Anne AziziDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0002-9226-9917
Noah BrookesDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Tong LanDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0003-3923-5408
Bryan C DickinsonDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0002-9616-1911
University of Chicago · US

Funding

MEDICAL SCIENTIST TRAININGT32GM007281 · NIGMS · UNIVERSITY OF CHICAGO · PI CLARK, MARCUS RAMSAY · 1985 to 2022
$32.1M
Rapid selection approaches to understand and reprogram proteins and peptidesR35GM119840 · NIGMS · UNIVERSITY OF CHICAGO · PI Bryan Dickinson · 2016 to 2026
$4.8M
Identifying the mechanisms and biological impact of ERK lipidation in metabolic signalingF30DK125088 · NIDDK · UNIVERSITY OF CHICAGO · PI AZIZI, SAARA-ANNE · 2020 to 2022
$153k
NIDDK NIH HHS F30 DK125088NIGMS NIH HHS R35 GM119840NIGMS NIH HHS T32 GM007281
6 · The paper itself

Abstract

As the "writer" enzymes of protein

Indexed as

AcyltransferasesHigh-Throughput Screening AssaysProtein Processing, Post-TranslationalAcyltransferases

Identifiers

PMID35816339
PMCPMC9391280
OpenAlexW4285014929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.