Evidence map›Paper›PMID 35816225›Full record

ArticleAnnals of intensive care2022

Clinical status of patients 1 year after hospital discharge following recovery from COVID-19: a prospective cohort study.

Dapeng Li, Xuejiao Liao, Zhenghua Ma, Lina Zhang, Jingke Dong, Guoqin Zheng, Mei Zi, Wujian Peng, Lanlan Wei, Zhiyan Li and 8 more

Abstract read
In one paragraph

Article in Annals of intensive care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. ERJ open research · 2024
    Article
  8. Review
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  11. Long-term interplay between COVID-19 and chronic kidney disease.International urology and nephrology · 2023
    Review
  12. CT findings in "Post-Covid": residua from acute pneumonia or "Post-Covid-ILD"?Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2023
    Article
  13. TheInternational journal of molecular sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Dapeng Li *Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Xuejiao Liao *Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Zhenghua MaDepartment of Chronic Disease Follow-Up, Shenzhen Third People's Hospital, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Lina ZhangDepartment of Chronic Disease Follow-Up, Shenzhen Third People's Hospital, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Jingke DongDepartment of Chronic Disease Follow-Up, Shenzhen Third People's Hospital, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Guoqin ZhengDepartment of Chronic Disease Follow-Up, Shenzhen Third People's Hospital, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Mei ZiDepartment of Respiratory Medicine, Shenzhen Third People's Hospital, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Wujian PengDepartment of Nephrology, Shenzhen Third People's Hospital, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Lanlan WeiInstitute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Zhiyan LiDepartment of Ultrasound, Shenzhen Third People's Hospital, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Yingjun KongDepartment of Respiratory Medicine, Shenzhen Third People's Hospital, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Lifei WangDepartment of Radiology, Shenzhen Third People's Hospital, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Dongjing LiuInstitute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Fang WangInstitute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China.
Qing HeInstitute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China. heqingjoe@163.com.
Guobao LiDepartment of the Third Pulmonary Disease, Shenzhen Third People's Hospital, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China. l3gb@qq.com.
Zheng ZhangInstitute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China. zhangzheng1975@aliyun.com.ORCID http://orcid.org/0000-0002-3544-1389
Lei LiuInstitute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, No. 29, Bulan Road, Longgang district, Shenzhen, 518112, China. liulei3322@aliyun.com.

Funding

Central Charity Fund of Chinese Academy of Medical Science 2020-PT310-009Emergency Key Program of Guangzhou Laboratory EKPG21-29National Science Fund for Distinguished Young Scholars 82025022Science and Technology Innovation Committee of Shenzhen Municipality JSGG20200207155251653Science and Technology Innovation Committee of Shenzhen Municipality JSGG20200225152848007Science and Technology Innovation Committee of Shenzhen Municipality JSGG20220226090002003
6 · The paper itself

Abstract

backgroundThe long-term clinical status of coronavirus disease 2019 (COVID-19) in recovered patients remains largely unknown. This prospective cohort study evaluated clinical status of COVID-19 and explored the associated risk factors.

methodsAt the outpatient visit, patients underwent routine blood tests, physical examinations, pulmonary function tests, 6-min walk test, high-resolution computed tomography (CT) of the chest, and extrapulmonary organ function tests.

results230 patients were analyzed. Half (52.7%) reported at least one symptom, most commonly fatigue (20.3%) and sleep difficulties (15.8%). Anxiety (8.2%), depression (11.3%), post-traumatic symptoms (10.3%), and sleep disorders (26.3%) were also reported. Diffusion impairments were found in 35.4% of the patients. Abnormal chest CT scans were present in 63.5% of the patients, mainly reticulation and ground-glass opacities. Further, a persistent decline in kidney function was observed after discharge. SARS-CoV-2-specific antibodies of IgA, IgG, and IgM were positive in 56.4%, 96.3%, and 15.2% of patients, respectively. Multivariable logistic regression showed that disease severity, age, and sex were closely related to patient recovery.

conclusionsOne year after hospital discharge, patients recovered from COVID-19 continued to experience both pulmonary and extrapulmonary dysfunction. While paying attention to pulmonary manifestations of COVID-19, follow-up studies on extrapulmonary manifestations should be strengthened.

Indexed as

COVID-19Extrapulmonary dysfunctionPulmonary dysfunctionRisk factorSARS-CoV-2 antibodies

Identifiers

PMID35816225
PMCPMC9272871

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.