ArticleInvestigative ophthalmology & visual science2022
Effects of Monocular Light Deprivation on the Diurnal Rhythms in Retinal and Choroidal Thickness.
Article in Investigative ophthalmology & visual science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Lens opacity as a predictor of retinal vasculature change following cataract surgery.Scientific reports · 2025Article
- Axial Length Dynamics and Safety of Occlusion Therapy in Pediatric Amblyopia: A Longitudinal Analysis.Investigative ophthalmology & visual science · 2025Article
- Twenty-four hour diurnal variation in retinal oxygen saturation.Vision research · 2023Article
- Impact of Phacoemulsification Parameters on Central Retinal Thickness Change Following Cataract Surgery.Diagnostics (Basel, Switzerland) · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Purpose: To determine the effects of monocular light deprivation on diurnal rhythms in retinal and choroidal thickness. Methods: Twenty participants, ages 22 to 45 years, underwent spectral domain optical coherence tomography imaging every three hours, from 8 AM to 8 PM, on two consecutive days. Participants wore an eye patch over the left eye starting at bedtime of day 1 until the end of the last measurement on day 2. Choroidal, total retinal, photoreceptor outer segment + retinal pigment epithelium (RPE), and photoreceptor inner segment thicknesses were determined. Results: For both eyes, significant diurnal variations were observed in choroidal, total retinal, outer segment + RPE, and inner segment thickness (P < 0.001). For light-deprived eyes, choroid diurnal variation persisted, although the choroid was significantly thinner at 8 AM and 11 AM (P < 0.01) on day 2 compared to day 1. On the other hand, diurnal variations in retinal thickness were eliminated in the light-deprived eye on day 2 when the eye was patched (P > 0.05). Total retinal and inner segment thicknesses significantly decreased (P < 0.001) and outer segment + RPE thickness significantly increased (P < 0.05) on day 2 compared to day 1. Conclusions: Blocking light exposure in one eye abolished the rhythms in retinal thickness, but not in choroidal thickness, of the deprived eye. Findings suggest that the rhythms in retinal thickness are, at least in part, driven by light exposure, whereas the rhythm in choroidal thickness is not impacted by short-term light deprivation.
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