ReviewJournal of intensive care medicine2022
To Wean or Not to Wean: A Practical Patient Focused Guide to Ventilator Weaning.
Review in Journal of intensive care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mechanical Power As a Predictor for Weaning in Chronic Obstructive Pulmonary Disease Patients :Prospective Cohort Study.
Mechanical Power Versus Diaphragmatic Excursion As a Predictor for Weaning in Chronic Obstructive Pulmonary Disease Patients: Prospective Cohort Study
Who cites it
25 citing papers in PubMed, 50 citations in OpenAlex.
- The therapeutic effect of levosimendan in patients with prolonged ventilator weaning and cardiac dysfunction.The Journal of international medical research · 2024Trial
- Key Characteristics and Mechanisms in Ventilator Weaning of Adult Intensive Care Patients-A Qualitative Study With Healthcare Professionals.Nursing in critical care · 2026Article
- Machine learning models predicting extubation success in mechanically ventilated patients: a systematic review and meta-analysis.Intensive care medicine experimental · 2026Review
- Diaphragmatic Ultrasound Parameters as Predictors of Weaning Success in Cervical Spinal Cord Injury.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Developing a Program Theory on Ventilator Weaning in Adult Intensive Care: Protocol for a Multimethods Study.JMIR research protocols · 2026Article
- Efficacy and safety of sedation induced with cipepofol alone versus a dexmedetomidine plus propofol regimen for patients requiring mechanical ventilation: a randomized, open-label, non-inferiority trial.Annals of intensive care · 2026Article
- Assessment of Respiratory Mechanics and Inspiratory Effort During Spontaneous Breathing Trials to Predict Extubation Failure in High-Risk Patients.American journal of respiratory and critical care medicine · 2025Article
- Real-Time Predictive Analysis of ICU Ventilator Weaning Failure: A Prospective Validation Study.The clinical respiratory journal · 2025Article
- Healthcare 5.0-Driven Clinical Intelligence: The Learn-Predict-Monitor-Detect-Correct Framework for Systematic Artificial Intelligence Integration in Critical Care.Healthcare (Basel, Switzerland) · 2025Review
- Assessment of the Rapid Shallow Breathing Index, Integrative Weaning Index, and Dead Space to Tidal Volume Ratio by Respiratory Failure Type in Successfully Weaned Emergency Department Patients.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- SARS-CoV-2 Pneumonia: Advances in Diagnosis and Treatment.Microorganisms · 2025Review
- Integration of Diaphragmatic Ultrasonography and Intra-Abdominal Pressure Measurement for Optimizing Weaning from Mechanical Ventilation.Risk management and healthcare policy · 2025Article
- Construction and evaluation of a machine learning-based predictive model for enteral nutrition feeding intolerance risk in ICU patients.Frontiers in nutrition · 2025Article
- Heart Rate Variability During Weaning from Invasive Mechanical Ventilation: A Systematic Review.Journal of clinical medicine · 2024Review
- Let It Breathe: Mastering Spontaneous Breathing Trials.Respiratory care · 2024Article
- Weaning Failure in Elderly Patients: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Time course of electrical activity of the diaphragm (EAdi) in the peri extubation period and its role as predictor of extubation failure in difficult to wean patients.Critical care (London, England) · 2024Observational
- Physical and respiratory therapy in the critically ill patient with obesity: a narrative review.Frontiers in medicine · 2024Review
- 2022 Year in Review: Ventilator Liberation.Respiratory care · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Since the inception of critical care medicine and artificial ventilation, literature and research on weaning has transformed daily patient care in intensive care units (ICU). As our knowledge of mechanical ventilation (MV) improved, so did the need to study patient-ventilator interactions and weaning predictors. Randomized trials have evaluated the use of protocol-based weaning (vs. usual care) to study the duration of MV in ICUs, different techniques to conduct spontaneous breathing trials (SBT), and strategies to eventually extubate a patient whose initial SBT failed. Despite considerable milestones in the management of multiple diseases contributing to reversible respiratory failure, in the application of early rehabilitative interventions to preserve muscle integrity, and in ventilator technology that mitigates against ventilator injury and dyssynchrony, major barriers to successful liberation from MV persist. This review provides a broad encompassing view of weaning classification, causes of weaning failure, and evidence behind weaning predictors and weaning modes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.