Evidence map›Paper›PMID 35815706›Full record

ArticleDrug delivery2022

Oxaliplatin-loaded nanoemulsion containing

Waad A Al-Otaibi, Sahar M AlMotwaa

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Nanoemulsions in Skin Cancer Therapy: A Promising Frontier.Current pharmaceutical biotechnology · 2025
    Review
  5. Article
  6. Article
  7. Antioxidants (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Co-Delivery of Ylang Ylang Oil ofInternational journal of molecular sciences · 2023
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Waad A Al-OtaibiDepartment of Chemistry, College of Science and Humanities, Shaqra University, Shaqra, Saudi Arabia.ORCID 0000-0002-7341-4832
Sahar M AlMotwaaDepartment of Chemistry, College of Science and Humanities, Shaqra University, Shaqra, Saudi Arabia.ORCID 0000-0003-1378-7140
Shaqra University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxaliplatin (Oxa)-associated adverse side effects have considerably limited the clinical use of the drug in colon cancer therapy. Mutant p53 has diverse mutational profiles in colon cancer, and it influences the potencies of various chemotherapeutic drugs, including Oxa. Thus, it would be highly beneficial to identify an alternative therapeutic strategy that not only reduces the toxicity of Oxa, but also exerts a synergistic effect against colon cancers, regardless of their p53 profiles. The present study was aimed at preparing and optimizing

Indexed as

Colonic NeoplasmsOils, VolatileTeucriumApoptosisCell Line, TumorHCT116 CellsHT29 CellsHumansOxaliplatinReactive Oxygen SpeciesTumor Suppressor Protein p53Oils, VolatileOxaliplatinReactive Oxygen SpeciesTumor Suppressor Protein p53Combination therapyflow cytometrynano-delivery systemnanoemulsionOxaliplatinReactive oxygen speciesROS-mediated mitochondrial apoptosisTeucrium polium L. essential oil

Identifiers

PMID35815706
PMCPMC9278420
OpenAlexW4285005741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.