Evidence map›Paper›PMID 35815640›Full record

SynthesisEpidemiology and psychiatric sciences2022

Who benefits from individual placement and support? A meta-analysis.

Lars de Winter, Chrisje Couwenbergh, Jaap van Weeghel, Sarita Sanches, Harry Michon, Gary R Bond

Abstract readMeta-Analysis
In one paragraph

Synthesis in Epidemiology and psychiatric sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lars de WinterPhrenos Center of Expertise for Severe Mental Illnesses, Utrecht, the Netherlands.ORCID https://orcid.org/0000-0002-0523-3204
Chrisje CouwenberghPhrenos Center of Expertise for Severe Mental Illnesses, Utrecht, the Netherlands.
Jaap van WeeghelPhrenos Center of Expertise for Severe Mental Illnesses, Utrecht, the Netherlands.
Sarita SanchesPhrenos Center of Expertise for Severe Mental Illnesses, Utrecht, the Netherlands.
Harry MichonMovisie Netherlands Centre for Social Development, Utrecht, the Netherlands.
Gary R BondWestat, Lebanon, NH, USA.ORCID https://orcid.org/0000-0003-1587-9823

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsIndividual placement and support (IPS) is an evidence-based service model to support people with mental disorders in obtaining and sustaining competitive employment. IPS is increasingly offered to a broad variety of service users. In this meta-analysis we analysed the relative effectiveness of IPS for different subgroups of service users both based on the diagnosis and defined by a range of clinical, functional and personal characteristics.

methodsWe included randomised controlled trials that evaluated IPS for service users diagnosed with any mental disorder. We examined effect sizes for the between-group differences at follow-up for three outcome measures (employment rate, job duration and wages), controlling for methodological confounders (type of control group, follow-up duration and geographic region). Using sensitivity analyses of subgroup differences, we analysed moderating effects of the following diagnostic, clinical, functional and personal characteristics: severe mental illness (SMI), common mental disorders (CMD), schizophrenia spectrum disorders, mood disorders, duration of illness, the severity of symptoms, level of functioning, age, comorbid alcohol and substance use, education level and employment history.

resultsIPS is effective in improving employment outcomes compared to the control group in all subgroups, regardless of any methodological confounder. However, IPS was relatively more effective for service users with SMIs, schizophrenia spectrum disorders and a low symptom severity. Although IPS was still effective for people with CMD and with major depressive disorder, it was relatively less effective for these subgroups. IPS was equally effective after both a short and a long follow-up period. However, we found small, but clinically not meaningful, differences in effectiveness of IPS between active and passive control groups. Finally, IPS was relatively less effective in European studies compared to non-European studies, which could be explained by a potential benefits trap in high welfare countries.

conclusionsIPS is effective for all different subgroups, regardless of diagnostic, clinical, functional and personal characteristics. However, there might be a risk of false-positive subgroup outcomes and results should be handled with caution. Future research should focus on whether, and if so, how the IPS model should be adapted to better meet the vocational needs of people with CMD and higher symptom severity.

Indexed as

Employment, SupportedMajor Depressive DisorderMental DisordersSchizophreniaSubstance-Related DisordersHumansRehabilitation, VocationalMental healthrandomised controlled trialsrehabilitationsystematic reviews

Identifiers

PMID35815640
PMCPMC9281491

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.