Evidence map›Paper›PMID 35815566›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2022

Dyhidro-β-agarofurans natural and synthetic as acetylcholinesterase and COX inhibitors: interaction with the peripheral anionic site (AChE-PAS), and anti-inflammatory potentials.

Julio Alarcón-Enos, Evelyn Muñoz-Núñez, Margarita Gutiérrez, Soledad Quiroz-Carreño, Edgar Pastene-Navarrete, Carlos Céspedes Acuña

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Isolation and Identification of Phytocompounds fromMolecules (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julio Alarcón-EnosDepartamento de Ciencias Básicas, Universidad del Bío-Bío, Chillán, Chile.
Evelyn Muñoz-NúñezDepartamento de Ciencias Básicas, Universidad del Bío-Bío, Chillán, Chile.
Margarita GutiérrezInstituto de Química, Universidad de Talca, Talca, Chile.
Soledad Quiroz-CarreñoDepartamento de Ciencias Básicas, Universidad del Bío-Bío, Chillán, Chile.
Edgar Pastene-NavarreteDepartamento de Ciencias Básicas, Universidad del Bío-Bío, Chillán, Chile.
Carlos Céspedes AcuñaDepartamento de Ciencias Básicas, Universidad del Bío-Bío, Chillán, Chile.ORCID 0000-0002-3715-3268

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to find molecules of natural origin with potential biological activities, we isolate and synthesise compounds with agarofuran skeletons (epoxyeudesmanes). From the seeds of

Indexed as

AcetylcholinesteraseAlzheimer DiseaseAnti-Inflammatory AgentsCatalytic DomainCholinesterase InhibitorsHumansMolecular Docking SimulationStructure-Activity RelationshipAcetylcholinesteraseAnti-Inflammatory AgentsCholinesterase InhibitorsAcetylcholinesteraseAlzheimer’s diseasebutyrylcholinesteraseCOX-2dihydro-β-agarofuransmolecular docking

Identifiers

PMID35815566
PMCPMC9278454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.