Evidence map›Paper›PMID 35815457›Full record

ArticleJournal of medical virology2022

Clinical presentations of adult and pediatric SARS-CoV-2-positive cases in a community cohort, Nashville, Tennessee.

Danielle A Rankin, Ahmad Yanis, Rana Talj, Harrison L Howe, Sean M Bloos, Kailee N Fernandez, Justin Z Amarin, Mercedes Bruce, Seifein Salib, Samarian Hargrave and 4 more

Abstract read
In one paragraph

Article in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Danielle A RankinDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0003-3018-3373
Ahmad YanisDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Rana TaljDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Harrison L HoweDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Sean M BloosDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Kailee N FernandezDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Justin Z AmarinDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-4484-1077
Mercedes BruceDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Seifein SalibDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Samarian HargraveDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
James D ChappellDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Andrew J SpiekerDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Natasha B HalasaDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-6381-1826
Leigh M HowardDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
NRSA Training CoreTL1TR002244 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$4.6M
Pneumococcal dynamics in the conjugate vaccine era: Addressing unanswered questionsK23AI141621 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HOWARD, LEIGH MEREDITH · 2019 to 2022
$736k
NCATS NIH HHS TL1 TR002244NCATS NIH HHS UL1 TR000445NIAID NIH HHS K23 AI141621NIH HHS
6 · The paper itself

Abstract

Compared to adults, the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) illness in children has been lower and less severe. However, reports comparing SARS-CoV-2 infection among children and adults are limited. As part of our longitudinal cohort study of adults and children with SARS-CoV-2 infection and their household contacts in Nashville, Tennessee, we compared the clinical characteristics and outcomes of SARS-CoV-2 infections between children and adults. Children were more likely to be asymptomatically infected and had a shorter illness duration compared to adults. The differences observed in clinical presentation across ages may inform symptom-specific testing, screening, and management algorithms.

Indexed as

COVID-19SARS-CoV-2AdultChildCOVID-19 TestingHumansLongitudinal StudiesTennesseeCOVID-19 in adultspediatric COVID-19SARS-CoV-2-positive adultsSARS-CoV-2-positive children

Identifiers

PMID35815457
PMCPMC9350274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.