Evidence map›Paper›PMID 35815426›Full record

ArticleMolecular pain2022

Analgesic effect of gastrin-releasing peptide in the dorsal horn.

Ayano Saeki, Hiroki Yamanaka, Kimiko Kobayashi, Masamichi Okubo, Koichi Noguchi

Open access · goldAbstract read
In one paragraph

Article in Molecular pain, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ayano SaekiDepartment of Anatomy and Neuroscience, Faculty of Medicine, 12818Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Hiroki YamanakaDepartment of Anatomy and Neuroscience, Faculty of Medicine, 12818Hyogo Medical University, Nishinomiya, Hyogo, Japan.ORCID 0000-0002-0604-0551
Kimiko KobayashiDepartment of Anatomy and Neuroscience, Faculty of Medicine, 12818Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Masamichi OkuboDepartment of Anatomy and Neuroscience, Faculty of Medicine, 12818Hyogo Medical University, Nishinomiya, Hyogo, Japan.ORCID 0000-0001-8097-4304
Koichi NoguchiDepartment of Anatomy and Neuroscience, Faculty of Medicine, 12818Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Hyogo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Itch and pain are both unpleasant, but they are discrete sensations. Both of these sensations are transmitted by C-fibers and processed in laminae I-II of the dorsal horn. To examine whether pruriception modulates pain, we first confirmed the activation of cells in the itch-related circuits that were positive for gastrin-releasing peptide (GRP) and GRP receptor (GRPR) using a paw formalin injection model. This pain model with typical biphasic pain behavior increased c-Fos but did not affect the expressions of

Indexed as

PruritusReceptors, BombesinAnalgesicsFormaldehydeGastrin-Releasing PeptideHumansNerve Fibers, UnmyelinatedPainPosterior Horn CellsSpinal CordSpinal Cord Dorsal HornAnalgesicsFormaldehydeGastrin-Releasing PeptideReceptors, Bombesinc-Fosdorsal hornformalin testgastrin-releasing peptidegastrin-releasing peptide receptor neuronitch

Identifiers

PMID35815426
PMCPMC9277428
OpenAlexW4285007825

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.