ArticleAddiction (Abingdon, England)2023
Adolescent substance use and high school noncompletion: exploring the nature of the relationship using a discordant twin design.
Article in Addiction (Abingdon, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Medical Cannabis Use Across Ages 19-65 Years: U.S. Young and Middle Adults, 2018-2023.American journal of preventive medicine · 2026Article
- Patterns of Cannabis Use and Perceived Accessibility Among Underage U.S. Young Adults: Implications for Policy and Prevention.Journal of studies on alcohol and drugs · 2026Article
- Historical change in associations between perceived risk, disapproval, and use of cannabis among young adults ages 19-30, 2011-2022.Addictive behaviors · 2025Article
- Reasons for Vaping Among US Adolescents.Pediatrics · 2024Article
- Genetic and shared environmental factors explain the association between adolescent polysubstance use and high school noncompletion.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024Article
- Prospective associations between adolescent risky substance use and school dropout and the role of externalising and internalising problems.Nordisk alkohol- & narkotikatidskrift : NAT · 2024Article
- Age- and Sex-Varying Associations Between Depressive Symptoms and Substance Use from Modal Ages 35 to 55 in a National Sample of U.S. Adults.Prevention science : the official journal of the Society for Prevention Research · 2023Article
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Authors and funding
7 authors.
Funding
Abstract
BACKGROUND AND
aimsPrevious studies have demonstrated associations between substance use and reduced educational attainment; however, many were unable to account for potential confounding factors like genetics and the rearing environment. In the few studies that controlled for these factors, the substances assessed were limited to alcohol, cannabis, and tobacco. To address these limitations, we examined the relationship between adolescent use of seven kinds of substances, the number of additional substances used, and high school noncompletion within a large sample of Australian twins.
designA series of two-level generalized mixed effects logistic regressions were conducted to examine associations between adolescent substance use and high school noncompletion.
settingAustralia.
participantsA total of 9579 adult Australian twins from two cohorts of the Australian Twin Registry. MEASUREMENTS: Assessments of high school completion, childhood major depression, conduct disorder symptoms, substance use initiation, demographics, and parental educational attainment using the Australian version of the Semi-Structured Assessment for the Genetics of Alcoholism.
findingsThere were unique within-twin-pair effects of use of sedatives (odds ratio [OR] = 22.39 [95% confidence interval (CI) = 1.18-423.48]) and inhalants/solvents (OR = 10.46 [95% CI = 1.30-84.16]) on high school noncompletion. The number of substances used in adolescence was strongly associated with high school noncompletion across all discordant twin models (ORs from 1.50-2.32, Ps < 0.03).
conclusionsIn Australia, adolescent substance use appears to be associated with early school dropout, with the effects of any given substance largely because of the confounding factors of parental education, childhood conduct disorder symptoms, and use of other substances. Sedatives and inhalants/solvents have effects on high school noncompletion that cannot be explained by polysubstance use or familial factors.
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