Evidence map›Paper›PMID 35815301›Full record

ArticleCureus2022

Neuro Postural Optimization Neuromodulation Treatment of Radio Electric Asymmetric Conveyer Technology on Stress and Quality of Life in Institutionalized Children in a Capital City of the Brazilian Amazon.

Ana V Gonçalves de Oliveira Cruz, Rebeca Góes Gonçalves, Lucas Nunes, João Douglas Quaresma de Oliveira, Ester S Lima Monteiro, Italo Soares Eneias, Taynara C Guilherme Lima, Larissa Duarte Ferreira, Erick Souza Neri, José L da Cunha Pena and 5 more

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07373366 (Effects of Neurobiological Therapy With Asymmetric Radio-electric Conveyer), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07373366 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Neurobiological Therapy With Asymmetric Radio-electric Conveyer (REAC) in Diffuse Axonal Injury: a Randomized Controlled Trial.

TypeinterventionalSponsorUniversity of Sao PauloRan2025 to 2027Enrolled60ConditionsTraumatic Brain InjuryArmsSubjects in the intervention group receive low-frequency radioelectric therapy, Sham, the device simulates a therapy session
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Ana V Gonçalves de Oliveira CruzInstitutional Program for Scientific Initiation Scholarships (PIBIC), Federal University of Amapá (UNIFAP), Macapá, BRA.
Rebeca Góes GonçalvesInstitutional Scholarship Program for University Extension (PIBEX), Federal University of Amapá (UNIFAP), Macapá, BRA.
Lucas NunesInstitutional Program for Scientific Initiation Scholarships (PIBIC), Federal University of Amapá (UNIFAP), Macapá, BRA.
João Douglas Quaresma de OliveiraInstitutional Scholarship Program for University Extension (PIBEX), Federal University of Amapá (UNIFAP), Macapá, BRA.
Ester S Lima MonteiroScientific Initiation Scholarship-Affirmative Actions (PROBIC-AF), Federal University of Amapá (UNIFAP), Macapá, BRA.
Italo Soares EneiasFaculty of Medicine Department of Biological and Health Sciences (DCBS), Federal University of Amapá (UNIFAP), Macapá, BRA.
Taynara C Guilherme LimaPostgraduate Program in Health Sciences (PPGCS), Federal University of Amapá (UNIFAP), Macapá, BRA.
Larissa Duarte FerreiraPostgraduate Program in Health Sciences (PPGCS), Federal University of Amapá (UNIFAP), Macapá, BRA.
Erick Souza NeriScientific Initiation Scholarship-Affirmative Actions (PROBIC-AF), Federal University of Amapá (UNIFAP), Macapá, BRA.
José L da Cunha PenaPostgraduate Program in Health Sciences (PPGCS), Federal University of Amapá (UNIFAP), Macapá, BRA.
Anelli M Célis de CárdenasPostgraduate Program in Health Sciences (PPGCS), Federal University of Amapá (UNIFAP), Macapá, BRA.
Maria I Côrtes VolpePostgraduate Program in Health Sciences (PPGCS), Federal University of Amapá (UNIFAP), Macapá, BRA.
Maria V Filgueiras de Assis MeloFaculty of Nursing Department of Biological and Health Sciences (DCBS), Federal University of Amapá (UNIFAP), Macapá, BRA.
Arianna RinaldiResearch Department, Rinaldi Fontani Foundation, Florence, ITA.
Ana R Pinheiro BarcessatPostgraduate Program in Health Sciences (PPGCS), Federal University of Amapá (UNIFAP), Macapá, BRA.
Deutsches Historisches Institut Rom · ITUniversidade Federal do Amapá · BRUniversity of Sassari · ITInstitute of Neuroimmunology of the Slovak Academy of Sciences · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The deviation from perfect bilateral symmetry is defined as fluctuating asymmetry (FA) and is a common phenomenon among living organisms. This deviation from perfection is thought to reflect the environmental pressures experienced during development and, therefore, the FA represents an epigenetic measure of the environmental stress, which affects all living beings from conception, progressively affecting all aspects of life. Rinaldi and Fontani hypothesized that the FA morpho-functional changes are originated by an adaptive motor behavior determined by functional alterations in the cerebellum and neural circuits, not caused by a lesion, but induced by the experienced environmental stress. They identified in the asymmetric activation of symmetrical muscle groups, detectable even in healthy subjects, the expression of the dysfunctional adaptation state of the subject and named this clinical semeiotic phenomenon functional dysmetria (FD). On these premises, they developed the radio electric asymmetric conveyer (REAC) technology, a neuromodulation technology aimed at optimizing the best neuro-psycho-motor strategies in relation to environmental interaction. Neuro postural optimization (NPO) is a neurobiological stimulation treatment administered with the REAC technology and it has been specifically studied to treat the state of dysfunctional adaptation that is revealed through the presence of FD. Aim The purpose of this study was to verify whether a single administration of the REAC NPO treatment can trigger the improvement of the capacity of stress management and the quality of life in a population of children housed in a group home in Macapá, Brazil. Materials and methods The sample of this study consisted of nine children (six boys and three girls) in the age group of 6-11 years, which represented the totality of the children present in the structure. The children was investigated for the assessment of the presence of functional dysmetria and with the Pediatric Quality of Life Inventory TM 4.0 (PedsQL) before and one week after the administration of the REAC NPO. Results The stable disappearance of FD was found in all children at follow-up. In addition, improvements were found in stress management and quality of life, in the physical, emotional, social, and scholastic aspects evaluated with PedsQL. Conclusions It was seen that the REAC NPO neurobiological modulation treatment induced the stable disappearance of FD and triggered the initial improvement of neurophysical aspects also in a population of children housed in a group home in the Amazon region of Macapá, Brazil.

Indexed as

fluctuating asymmetryfunctional dysmetriainstitutionalized childrenneuromodulationneuro postural optimizationquality of lifequality of life improvementradioelectric asymmetric conveyerreac

Identifiers

PMID35815301
PMCPMC9256006
OpenAlexW4283797695

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.