Evidence map›Paper›PMID 35815187›Full record

ArticleBiomedical reports2022

Activated leukocyte cell adhesion molecule/cluster of differentiation 166 rs10933819 (G>A) variant is associated with familial intracranial aneurysms.

Akbota Aitkulova, Kymbat Mukhtarova, Elena Zholdybayeva, Yerkin Medetov, Botagoz Dzhamantayeva, Kuat Kassymbek, Talgat Utupov, Ilyas Akhmetollayev, Serik Akshulakov, Gulmira Kulmambetova and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Biomedical reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Akbota AitkulovaNational Center for Biotechnology, Nur Sultan 010000, Republic of Kazakhstan.
Kymbat MukhtarovaNational Center for Biotechnology, Nur Sultan 010000, Republic of Kazakhstan.
Elena ZholdybayevaNational Center for Biotechnology, Nur Sultan 010000, Republic of Kazakhstan.
Yerkin MedetovNational Center of Neurosurgery, Nazarbayev University, Nur Sultan 010000, Republic of Kazakhstan.
Botagoz DzhamantayevaNational Center of Neurosurgery, Nazarbayev University, Nur Sultan 010000, Republic of Kazakhstan.
Kuat KassymbekNational Center for Biotechnology, Nur Sultan 010000, Republic of Kazakhstan.
Talgat UtupovNational Center for Biotechnology, Nur Sultan 010000, Republic of Kazakhstan.
Ilyas AkhmetollayevNational Center for Biotechnology, Nur Sultan 010000, Republic of Kazakhstan.
Serik AkshulakovNational Center of Neurosurgery, Nazarbayev University, Nur Sultan 010000, Republic of Kazakhstan.
Gulmira KulmambetovaNational Center for Biotechnology, Nur Sultan 010000, Republic of Kazakhstan.
Yerlan RamankulovNational Center for Biotechnology, Nur Sultan 010000, Republic of Kazakhstan.
National Center for Biotechnology · KZNazarbayev University · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rupture of intracranial aneurysms (IAs) is the most common cause of subarachnoid hemorrhage (SAH). Currently, there is sufficient evidence to indicate that inflammatory responses contribute to aneurysm rupture. Moreover, the familial occurrence of SAH suggests that genetic factors may be involved in disease susceptibility. In the present study, a clinically proven case of IA in a patient who is a heterozygous mutation carrier of the activated leukocyte cell adhesion molecule (

Indexed as

familial intracranial aneurysmsmutationsingle-nucleotide variantsubarachnoid hemorrhagewhole-exome sequencingсase study

Identifiers

PMID35815187
PMCPMC9260160
OpenAlexW4281938683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.