ArticleFrontiers in psychiatry2022
Impaired Oxygenation of the Prefrontal Cortex During Verbal Fluency Task in Young Adults With Major Depressive Disorder and Suicidality: A Functional Near-Infrared Spectroscopy Study.
Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Article
- Expectation Violation Influences Neural Responses to the Accessibility of Cognitions Related to Suicide and Life: A Simultaneous EEG-fNIRS Study.Brain sciences · 2026Article
- Utility of Functional Near-infrared Spectroscopy (fNIRS) in Major Depressive Disorder: A Systematic Review.Indian journal of psychological medicine · 2026Review
- Advanced imaging-integrated rTMS therapy for frontal network recovery after traumatic brain injury.Frontiers in human neuroscience · 2026Article
- Cortical dysfunction and impulsivity in non-suicidal self-injury: a multimodal study using TMS-EEG and fNIRS.Annals of medicine · 2025Article
- Classify the fNIRS signals of first-episode drug-naive MDD patients with or without suicidal ideation using machine learning.BMC psychiatry · 2025Article
- Augmented intermittent theta-burst stimulation of the left dorsolateral prefrontal cortex for cognitive dysfunction in stable-phase schizophrenia: protocol for a randomized, double-blind, sham-controlled trial.Frontiers in psychiatry · 2025Article
- Cortical activation for adolescent-onset minor depression and major depressive disorder: an fNIRS study.Annals of general psychiatry · 2024Article
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Authors and funding
8 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Few previous studies have focused on prefrontal activation in young adults diagnosed with major depressive disorder (MDD) and suicidality Materials and Methods: A total of 59 healthy controls (HCs), 35 patients with MDD but without suicidality, and 25 patients with MDD and suicidality, between the ages of 18-34 years, were enrolled. Changes in oxygenated hemoglobin (oxy-Hb) levels of the prefrontal cortex at baseline, 4 weeks, and 8 weeks, were evaluated using a protocol consisting of three consecutively repeated trials of rest, speech, and verbal fluency test (VFT) Results: Oxy-Hb levels were impaired in patients with MDD compared with HCs ( Conclusion: Impaired prefrontal oxygenation during cognitive execution may serve as a diagnostic biomarker for suicidality in young adult patients with MDD.
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