Evidence map›Paper›PMID 35814759›Full record

ArticleFrontiers in medicine2022

Serum Total Bilirubin With Hospital Survival in Adults During Extracorporeal Membrane Oxygenation.

Rui Huang, Min Shao, Cheng Zhang, Ming Fang, Mengmeng Jin, Xuan Han, Nian Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
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  4. Severe cholestasis in neonatal extracorporeal membrane oxygenation.The journal of extra-corporeal technology · 2025
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  6. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rui HuangDepartment of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Min ShaoDepartment of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Cheng ZhangAnhui Provincial Cancer Institute, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Ming FangDepartment of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Mengmeng JinDepartment of Respiratory and Critical Care, The Fourth Affiliated Hospital of Anhui Medical University, Hefei, China.
Xuan HanDepartment of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Nian LiuDepartment of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
First Affiliated Hospital of Anhui Medical University · CNAnhui Medical University · CNFourth Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Extracorporeal membrane oxygenation (ECMO) is widely used for refractory cardiopulmonary failure treatment. The disadvantage of ECMO is its higher risk profile and clinical resource consumption. This observation examines the role of serum total bilirubin (TBIL) as a predictor of adult patient outcomes on ECMO support. Methods: This retrospective observation reports a single-center experience with adults on ECMO support between 2018 and 2021. Data were collected regarding demographics, ECMO details, laboratory parameters, and outcomes. We examined the elevation of TBIL to predict survival and variables associated with hyperbilirubinemia. Results: The patients who died within 28 days had a twofold higher peak level of TBIL than those who survived [73.10 (38.60, 98.64) vs. 34.50 (24.03, 54.85); Conclusion: Serum total bilirubin elevation appears after ECMO initiation and correlates with survival, while other markers of liver injury do not. Serum total bilirubin is an easy-to-measure biomarker to be a predictor of survival after ECMO initiation.

Indexed as

extracorporeal membrane oxygenationhyperbilirubinemiaprognosissurvivaltotal bilirubin

Identifiers

PMID35814759
PMCPMC9263081
OpenAlexW4283370980

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.