Evidence map›Paper›PMID 35814519›Full record

ReviewJournal of clinical and experimental hepatology

Management of Portal Hypertension.

Anand V Kulkarni, Atoosa Rabiee, Arpan Mohanty

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Assessing portal hypertension and its impact on carbon emissions.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Article
  9. Article
  10. [Effects of ascites grading and the application of non-selective beta-blockers on the 1-year prognosis of acute-on-chronic liver failure].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Article
  11. Review
  12. Etiologies of Splenic Venous Hypertension: A Review.Journal of clinical and translational hepatology · 2024
    Review
  13. Review
  14. Review
  15. Article
  16. Updates in noncirrhotic portal hypertension.Clinical liver disease · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anand V KulkarniDepartment of Hepatology, AIG Hospitals, Hyderabad, India.
Atoosa RabieeVA Medical Center, Washington, DC, USA.
Arpan MohantyBoston University School of Medicine, Boston, MA, USA.
Washington DC VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Portal hypertension is the cause of the clinical complications associated with cirrhosis. The primary complications of portal hypertension are ascites, acute variceal bleed, and hepatic encephalopathy. Hepatic venous pressure gradient measurement remains the gold standard test for diagnosing cirrhosis-related portal hypertension. Hepatic venous pressure gradient more than 10 mmHg is associated with an increased risk of complications and is termed clinically significant portal hypertension (CSPH). Clinical, laboratory, and imaging methods can also aid in diagnosing CSPH non-invasively. Recently, deep learning methods have been demonstrated to diagnose CSPH effectively. The management of portal hypertension is always individualized and is dependent on the etiology, the availability of therapies, and the degree of portal hypertension complications. In this review, we discuss the diagnosis and management of cirrhosis-related portal hypertension in detail. Also, we highlight the history of portal hypertension and future research areas in portal hypertension.

Indexed as

ACLF, acute-on-chronic liver failureacute kidney injuryAKI, acute kidney injuryAPRI, AST to platelet ratioascitesAST, aspartate transaminaseBB, Beta blockerBRTO, balloon occluded retrograde transvenous obliterationCKD, chronic kidney diseaseCSPH, clinically significant portal hypertensionCT, computed tomographyGFR, glomerular filtration rateGOV, gastrpoesopahegal varicesHE, hepatic encephalopathyhemodynamicshistoryHRS, hepatorenal syndromeHVPG, hepatic venous pressure gradientICG, indocyanine greenLOLA, l-ornithine l-aspartateNAFLD, Non-alcoholic fatty liver diseaseSBP, spontaneous bacterial peritonitisSGLT2I, sodium glucose co-transporter 2 inhibitorsSSM, splenic stiffness measurementTE, transient elastographyTIPS, transjugular intrahepatic portosystemic shuntvasoconstrictorsVITRO, von Willebrand factor to platelet counts

Identifiers

PMID35814519
PMCPMC9257868
OpenAlexW4221073771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.