Evidence map›Paper›PMID 35814492›Full record

ReviewNorth American Spine Society journal2022

Clinical significance of concomitant pectus deformity and adolescent idiopathic scoliosis: systematic review with best evidence synthesis.

Laurian J M van Es, Barend J van Royen, Matthijs W N Oomen

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in North American Spine Society journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06009601 (Are Pectus Deformities a Projection of Spinal Pathologies?The Relationship Between Pectus Deformities and Spinal Pathologies), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06009601 completednot on this mapstarted 2023, after this paper: background citation

Are Pectus Deformities a Projection of Spinal Pathologies?The Relationship Between Pectus Deformities and Spinal Pathologies

TypeobservationalSponsorGaziosmanpasa Research and Education HospitalRan2023 to 2023Enrolled40ConditionsPectus Deformity of Chest, Spinal DeformityArmsPectus Study Form, Adams Test, Scoliosis Graphy, Pulmonary function test
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Diagnosis and Management of Pectus Excavatum in Primary Care.Journal of the American Board of Family Medicine : JABFM · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Laurian J M van EsDepartment of Orthopaedic Surgery, Noordwest Ziekenhuis, Wilhelminalaan 12 1815 JD Alkmaar, The Netherlands.
Barend J van RoyenDepartment of Orthopedic Surgery, Amsterdam UMC, University of Amsterdam and Vrije Universiteit, Amsterdam Movement Sciences, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
Matthijs W N OomenDepartment of Pediatric surgery, Amsterdam UMC, University of Amsterdam, Amsterdam Movement Sciences, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
Emma Kinderziekenhuis · NLNoordwest Ziekenhuisgroep · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A misbalance in forces is proposed for causing adolescent idiopathic scoliosis (AIS). AIS is therefore correlated to adjacent musculoskeletal pathologies. Its concomitance with idiopathic pectus deformities (PD) is underexposed. This systematic review analyzes the clinical significance and predictive factors of PD-associated AIS. Methods: A search was performed in PubMed, UpToDate, Embase, and Cochrane. A study was included if it: assessed the association between PD and scoliosis (category I), reported a prevalence of scoliosis in PD patients (category II), or addressed other topics about PD-associated AIS (category III). Studies in category I discussing predictive factors were appraised using the Quality in Prognosis Studies tool. Because of heterogeneity among the studies, predictive factors were analyzed according to a best evidence synthesis. A mean prevalence of scoliosis in PD patients was calculated using category I and II. Category III was narratively reviewed. Results: Forty-eight studies were included (I:19, II:21, III:8). Category I comprised 512 patients with PD-concomitant scoliosis. Thirteen studies reported predictive factors, of which 15 concerned the prevalence of scoliosis in PD patients and 12 Cobb Angle (CA) change after PD correction. Compared with AIS, PD seems to develop earlier in adolescence, and PD with concomitant AIS was more frequently reported in older patients. Evidence remained conflicting regarding the association between the severity of PD and that of scoliosis. As opposed to at a younger age, late PD correction is not associated with a postoperative increase of CA. Limited evidence showed that patients with a high CA undergoing PD correction do not experience an increase in CA, though, strong evidence indicated that it would not lead to a decrease in CA. The mean probable prevalence of AIS in PD patients was 13.1%. Conclusion: Current literature confirms the association between PD and AIS in patients with an indication for PD correction.

Indexed as

Adolescent idiopathic scoliosis (AIS)AIS, Adolescent Idiopathic ScoliosisBES, Best Evidence SynthesisBMI, Body Mass IndexCA, Cobb AngleChest wall deformitiesCT, Computed TomographyFunnel chestHI, Haller IndexPC, Pectus CarinatumPD, Pectus DeformityPectus carinatumPectus excavatumPE, Pectus ExcavatumPigeon breastScoliosisSTA, Sternal Tilt Angle

Identifiers

PMID35814492
PMCPMC9256832
OpenAlexW4283513423

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.