Evidence map›Paper›PMID 35814330›Full record

ArticleCurrent opinion in biomedical engineering2021

2D layered nanomaterials for therapeutics delivery.

Ryan Davis, Richard A Urbanowski, Akhilesh K Gaharwar

Abstract read
In one paragraph

Article in Current opinion in biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. NbRSC advances · 2026
    Article
  2. Article
  3. Designing the Next Generation of Biomaterials through Nanoengineering.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. DFT study of TiRSC advances · 2024
    Article
  10. Materials today. Bio · 2024
    Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Nano-bio interactions of 2D molybdenum disulfide.Advanced drug delivery reviews · 2022
    Review
  17. Review
  18. Advances in Biologically Applicable Graphene-Based 2D Nanomaterials.International journal of molecular sciences · 2022
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ryan DavisBiomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA.
Richard A UrbanowskiBiomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA.
Akhilesh K GaharwarBiomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA.

Funding

Mineralomics: Designing mineral based therapeutics to control and direct cell functionDP2EB026265 · NIBIB · TEXAS ENGINEERING EXPERIMENT STATION · PI GAHARWAR, AKHILESH K. · 2017 to 2021
$2.4M
IMSD at Texas A&M University: Initiative for Maximizing Student Diversity in Biomedical SciencesT32GM135748 · NIGMS · TEXAS A&M UNIVERSITY · PI BRINKMEYER-LANGFORD, CANDICE L., CHIU, WEIHSUEH A · 2020 to 2024
$1.2M
NIBIB NIH HHS DP2 EB026265NIGMS NIH HHS T32 GM135748
6 · The paper itself

Abstract

Two-dimensional (2D) nanomaterials are ultrathin, layered materials with a high surface-to-volume ratio that can deliver various therapeutics including small-molecule drugs, peptides, and large proteins. Their high surface area allows for high therapeutic loading and sustained therapeutic release over time. Some 2D nanomaterials respond to external stimuli, providing control over triggered or on-demand therapeutic release. 2D nanomaterials explored for biomedical applications include carbon-based (graphene), nanoclays, black phosphorous, layered double hydroxides, metal organic frameworks, covalent organic framework, 2D metal carbides and nitrides, transition metal dichalcogenides, transition metal oxides, polymer nanosheets, and hexagonal boron nitride. Most of these nanomaterials are biocompatible and degrade into nontoxic products, which is advantageous for therapeutic delivery systems. In this article, we will evaluate these nanomaterials for therapeutic delivery. We will highlight some of their unique physical and chemical characteristics, discuss their biological stability, and investigate their ability to deliver various therapeutics. Recent developments in 2D nanomaterials as drug delivery systems will also be discussed.

Indexed as

Drug deliveryEngineered nanomaterialsLayered nanomaterialsNanocarriersNanosheets

Identifiers

PMID35814330
PMCPMC9262334

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.