Evidence map›Paper›PMID 35814306›Full record

ArticleInternational journal of clinical practice2022

Association between Vitamin D Deficiency and Levels of Renin and Angiotensin in Essential Hypertension.

Lu Han, Xin-Juan Xu, Jun-Shi Zhang, Hai-Ming Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lu HanDepartment of Cardiology, The Armed Police Corps Hospital, Xinjiang, Urumqi 830000, China.
Xin-Juan XuDepartment of Hypertension, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0003-1934-8237
Jun-Shi ZhangDepartment of Hypertension, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Hai-Ming LiuDepartment of Hypertension, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Xinjiang Medical University · CNXinjiang Police College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The present study aims to investigate the relationship between vitamin D deficiency and renin-angiotensin-aldosterone levels in patients with essential hypertension. Methods: The present study observed two groups of patients from Urumqi, Xinjiang, China, from April 2017 to March 2018. There were two subject groups: the hypertension group (80 patients with essential hypertension selected by random cluster sampling) and the control group (76 healthy adults). The 25-hydroxyvitamin D (25(OH)D or vitamin D) levels were measured through electrolytes; fasting blood glucose, blood lipids, and other biochemical indicators were detected using immune chemiluminescence; and plasma renin activity and angiotensin II concentrations were detected with radio-immunity. Results: Comparison between the hypertension group and control group showed statistically significant differences in the systolic pressure and levels of 25(OH)D, renin, and triglycerides ( Conclusions: The results of the present study show that vitamin D deficiency is common in Urumqi, Xinjiang, China and vitamin D levels are negatively correlated with renin levels. Vitamin D plays an important role in regulating blood pressure by affecting renin levels through the renin-angiotensin-aldosterone system.

Indexed as

AngiotensinsEssential HypertensionReninVitamin D DeficiencyAdultAldosteroneAsian PeopleBlood PressureFemaleHumansMaleMiddle AgedAldosteroneAngiotensinsRenin

Identifiers

PMID35814306
PMCPMC9205726
OpenAlexW4281782803

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.