Evidence map›Paper›PMID 35814062›Full record

ArticleFrontiers in psychology2022

Age-Related Differences in Amygdala Activation Associated With Face Trustworthiness but No Evidence of Oxytocin Modulation.

Tian Lin, Didem Pehlivanoglu, Maryam Ziaei, Peiwei Liu, Adam J Woods, David Feifel, Håkan Fischer, Natalie C Ebner

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Neither inaccurate nor biased in later life: Age-related differences in the accuracy and bias of facial trustworthiness judgment.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Facial Trustworthiness Perception Across the Adult Life Span.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023
    Article
  8. Financial Fraud and Deception in Aging.Advances in geriatric medicine and research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Tian LinDepartment of Psychology, University of Florida, Gainesville, FL, United States.
Didem PehlivanogluDepartment of Psychology, University of Florida, Gainesville, FL, United States.
Maryam ZiaeiKavli Institute for Systems Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway.
Peiwei LiuDepartment of Psychology, University of Florida, Gainesville, FL, United States.
Adam J WoodsDepartment of Clinical and Health Psychology, Center for Cognitive Aging and Memory, University of Florida, Gainesville, FL, United States.
David FeifelDepartment of Psychiatry, University of California, San Diego, San Diego, CA, United States.
Håkan FischerDepartment of Psychology, University of Florida, Gainesville, FL, United States.
Natalie C EbnerDepartment of Psychology, University of Florida, Gainesville, FL, United States.
University of Florida · USNorwegian University of Science and Technology · NOStockholm University · SEUniversity of California, San Diego · US

Funding

UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
Characterizing and Modulating Neurocognitive Processes of Learning to Trust and Distrust in Aging (Diversity Supplement)R01AG072658 · NIA · UNIVERSITY OF FLORIDA · PI Natalie C Ebner, Nichole Lighthall · 2022 to 2026
$3.6M
Uncovering and Surveilling Financial Deception Risk in Aging (Diversity Supplement to 1R01AG057764-01A1)R01AG057764 · NIA · UNIVERSITY OF FLORIDA · PI EBNER, NATALIE C, SPRENG, ROBERT NATHAN · 2018 to 2022
$2.5M
Mechanisms of Oxytocin's Analgesia in Older Adults (Diversity Supplement)R01AG059809 · NIA · UNIVERSITY OF FLORIDA · PI CRUZ-ALMEIDA, YENISEL, EBNER, NATALIE C · 2018 to 2022
$1.8M
Research Network on Decision Neuroscience and AgingR24AG039350 · NIA · STANFORD UNIVERSITY · PI CARSTENSEN, LAURA L · 2010 to 2014
$896k
NCATS NIH HHS UL1 TR000064NIA NIH HHS R01 AG057764NIA NIH HHS R01 AG059809NIA NIH HHS R01 AG072658NIA NIH HHS R24 AG039350
6 · The paper itself

Abstract

The amygdala has been shown to be responsive to face trustworthiness. While older adults typically give higher face trustworthiness ratings than young adults, a direct link between amygdala response and age-related differences in face trustworthiness evaluation has not yet been confirmed. Additionally, there is a possible modulatory role of the neuropeptide oxytocin in face trustworthiness evaluation, but the results are mixed and effects unexplored in aging. To address these research gaps, young, and older adults were randomly assigned to oxytocin or placebo self-administration

Indexed as

agingamygdalaface trustworthinessfMRIoxytocin

Identifiers

PMID35814062
PMCPMC9262048
OpenAlexW4283310845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.