ArticleCurrent epidemiology reports2020
Trends in the public health significance, definitions of disease, and implications for prevention of Alzheimer's disease.
Article in Current epidemiology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Advancing dementia-friendly hospital care: a systematic review of healthcare professionals' reported barriers and facilitators using the theoretical domains framework.Age and ageing · 2026Pooled it
- Ficus deltoidea Preserves Hippocampal Neuronal Integrity and Redox Balance in Oxidative Stress-Driven Alzheimer's Disease-Like Rat Model.Molecular neurobiology · 2026Article
- Demographic trends in mortality related to Alzheimer's disease and pneumonia: a two-decade (1999-2022) analysis from the CDC WONDER database.Annals of medicine and surgery (2012) · 2026Article
- Alzheimer's Disease and Oral Health from Clinical Challenges to Interdisciplinary Care: A Narrative Review.Journal of clinical medicine · 2025Review
- Comparing Short Cognitive Screening Instruments in an Outreach Memory Clinic in Primary Care.International journal of environmental research and public health · 2025Article
- Oral Health Status and Factors Associated with Oral Health in Patients with Alzheimer's Disease: A Matched Case-Control Observational Study.Journal of clinical medicine · 2025Article
- Efficient Pause Extraction and Encode Strategy for Alzheimer's Disease Detection Using Only Acoustic Features from Spontaneous Speech.Brain sciences · 2023Article
- Protective effects ofNutrition research and practice · 2022Article
- Research Progress on Mechanism of Neuroprotective Roles of Apelin-13 in Prevention and Treatment of Alzheimer's Disease.Neurochemical research · 2022Review
- Constructing brain functional network by Adversarial Temporal-Spatial Aligned Transformer for early AD analysis.Frontiers in neuroscience · 2022Article
- Review
- Advancements in Imaging Technologies and AI Integration for Neurodegenerative Disease Management: A Narrative Review.Molecular imagingReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Purpose: Although Alzheimer's disease (AD) was described over a century ago, there remains no cure, and with the global demographic shift to older ages, the impact is increasing rapidly. This article summarizes how the conceptualization of AD has evolved in response to research advances. Current challenges, including the impact of multimorbidity are outlined and potential targets for prevention are discussed. Recent Findings: The ability to study AD neuropathology in vivo and results from longitudinal epidemiologic studies have led to a consensus that AD has a long preclinical course spanning decades. This view is driving efforts to identify early markers that will identify individuals at risk for AD dementia. Summary: Critical questions remain regarding the pathological mechanisms underlying AD and their relation to clinical symptoms. Nevertheless, evidence suggests that interventions targeting modifiable risk factors may slow or prevent the onset of disease while the search for a cure continues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.