Evidence map›Paper›PMID 35813693›Full record

ArticleCase reports in oncology

Large Parathyroid Tumor 8 Years after Thyroid Surgery: A Case Report.

Madara Ratniece, Elina Tauvena, Sergejs Pavlovics, Rita Niciporuka, Mara Liepa, Peteris Prieditis, Arturs Ozolins, Janis Gardovskis, Maija Radzina, Zenons Narbuts

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PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Madara RatnieceRadiology Research Laboratory, Riga Stradins University, Riga, Latvia.
Elina TauvenaFaculty of Medicine, Riga Stradins University, Riga, Latvia.
Sergejs PavlovicsRadiology Research Laboratory, Riga Stradins University, Riga, Latvia.
Rita NiciporukaDepartment of Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Mara LiepaRadiology Research Laboratory, Riga Stradins University, Riga, Latvia.
Peteris PrieditisRadiology Research Laboratory, Riga Stradins University, Riga, Latvia.
Arturs OzolinsDepartment of Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Janis GardovskisDepartment of Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Maija RadzinaRadiology Research Laboratory, Riga Stradins University, Riga, Latvia.
Zenons NarbutsDepartment of Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Pauls Stradiņš Clinical University Hospital · LVRiga Stradiņš University · LV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report represents an unusually large parathyroid carcinoma (PC) mimicking thyroid nodule recurrence after hemithyroidectomy. PC is a rare endocrine malignancy accounting for less than 1% of hyperparathyroidism cases. This is the first case report where contrast-enhanced ultrasound (CEUS) was performed on a PC. A 63-year-old female presented with an enlarged mass on the left side of the neck. In 2012, left-side hemithyroidectomy was done due to a benign goiter. In 2020, laboratory analysis showed markedly elevated parathyroid hormone and calcium. Multiparametric neck ultrasonography was performed including B-mode, color Doppler, shear wave elastography, and CEUS. Computed tomography revealed an irregular mass in proximity to the trachea, esophagus, and dislocation of the common carotid artery. Perifocal fatty tissue appeared normal. Scintigraphy displayed a suspected parathyroid tumor or a suspected left lobe nodule of thyroid. Based on the biochemical diagnosis of primary hyperparathyroidism and radiological examinations, a suspected parathyroid tumor was considered. Intraoperative findings demonstrated an unusually large 9 × 6 cm tumor (84 g) adjacent to the common carotid artery anterolaterally and the recurrent laryngeal nerve medially. Pathohistological examination revealed a tumor solid in structure, with focal necrosis penetrating the capsule. Immunohistochemical analysis was positive for chromogranin, CD56, and Ki-67 (8-10%) and negative for CK20 and CK7. The morphological and immunohistochemical results correspond to PC. PC is a challenging diagnosis requiring a multidisciplinary approach, especially in the case of previous neck surgery. The only curative treatment for PC is radical surgery. Lifelong monitoring of PCs is mandatory due to the high recurrence rate.

Indexed as

Contrast-enhanced ultrasoundHyperparathyroidismParathyroid carcinomaParathyroid hormoneParathyroid surgery

Identifiers

PMID35813693
PMCPMC9209974
OpenAlexW4280489905

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.