Evidence map›Paper›PMID 35813501›Full record

ReviewFrontiers in cellular neuroscience2022

Neuroprotective and Neurotoxic Effects of Glial-Derived Exosomes.

Karina Oyarce, María Yamila Cepeda, Raúl Lagos, Camila Garrido, Ana María Vega-Letter, María Garcia-Robles, Patricia Luz-Crawford, Roberto Elizondo-Vega

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 44 citations in OpenAlex.

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  18. Nano-structured strategies in combatting neurodegeneration.Frontiers in bioengineering and biotechnology · 2025
    Review
  19. Understanding AβMetabolic brain disease · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Karina OyarceLaboratorio de Neuroinmunología, Facultad de Medicina y Ciencia, Universidad San Sebastián, Concepción, Chile.
María Yamila CepedaLaboratorio de Neuroinmunología, Facultad de Medicina y Ciencia, Universidad San Sebastián, Concepción, Chile.
Raúl LagosLaboratorio de Biología Celular, Departamento de Biología Celular, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
Camila GarridoLaboratorio de Neuroinmunología, Facultad de Medicina y Ciencia, Universidad San Sebastián, Concepción, Chile.
Ana María Vega-LetterFacultad de Medicina, Centro de Investigación Biomédica, Universidad de los Andes, Santiago, Chile.
María Garcia-RoblesLaboratorio de Biología Celular, Departamento de Biología Celular, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
Patricia Luz-CrawfordFacultad de Medicina, Centro de Investigación Biomédica, Universidad de los Andes, Santiago, Chile.
Roberto Elizondo-VegaLaboratorio de Biología Celular, Departamento de Biología Celular, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
San Sebastián University · CLUniversity of Concepción · CLUniversidad de Los Andes, Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes derived from glial cells such as astrocytes, microglia, and oligodendrocytes can modulate cell communication in the brain and exert protective or neurotoxic effects on neurons, depending on the environmental context upon their release. Their isolation, characterization, and analysis under different conditions

Indexed as

astrocytesexosomesmicroglianeuroinflammationneuroprotectiveneurotoxicoligodendrocyte

Identifiers

PMID35813501
PMCPMC9257100
OpenAlexW4283369562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.