Evidence map›Paper›PMID 35813219›Full record

Article... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics2021

A Machine Learning Approach to Predict Acute Ischemic Stroke Thrombectomy Reperfusion using Discriminative MR Image Features.

Haoyue Zhang, Jennifer Polson, Kambiz Nael, Noriko Salamon, Bryan Yoo, William Speier, Corey Arnold

Open access · greenAbstract read
In one paragraph

Article in ... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Haoyue ZhangDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Jennifer PolsonDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Kambiz NaelDepartment of Radiology, University of California, Los Angeles, Los Angeles, CA, USA.
Noriko SalamonDepartment of Radiology, University of California, Los Angeles, Los Angeles, CA, USA.
Bryan YooDepartment of Radiology, University of California, Los Angeles, Los Angeles, CA, USA.
William SpeierDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Corey ArnoldDepartments of Bioengineering, Radiology, and Pathology, University of California, Los Angeles, Los Angeles, CA, USA.
University of California, Los Angeles · US

Funding

Medical Imaging Informatics Training GrantT32EB016640 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ALEX BUI, William Hsu · 2013 to 2026
$2.3M
A Machine Learning Approach to Classifying Time Since Stroke using Medical ImagingR01NS100806 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARNOLD, COREY WELLS · 2018 to 2022
$2.2M
NIBIB NIH HHS T32 EB016640NINDS NIH HHS R01 NS100806
6 · The paper itself

Abstract

Mechanical thrombectomy (MTB) is one of the two standard treatment options for Acute Ischemic Stroke (AIS) patients. Current clinical guidelines instruct the use of pretreatment imaging to characterize a patient's cerebrovascular flow, as there are many factors that may underlie a patient's successful response to treatment. There is a critical need to leverage pretreatment imaging, taken at admission, to guide potential treatment avenues in an automated fashion. The aim of this study is to develop and validate a fully automated machine learning algorithm to predict the final modified thrombolysis in cerebral infarction (mTICI) score following MTB. A total 321 radiomics features were computed from segmented pretreatment MRI scans for 141 patients. Successful recanalization was defined as mTICI score >= 2c. Different feature selection methods and classification models were examined in this study. Our best performance model achieved 74.42±2.52% AUC, 75.56±4.44% sensitivity, and 76.75±4.55% specificity, showing a good prediction of reperfusion quality using pretreatment MRI. Results suggest that MR images can be informative to predicting patient response to MTB, and further validation with a larger cohort can determine the clinical utility.

Indexed as

Machine LearningRadiomicsStroke TreatmentStructural MRI

Identifiers

PMID35813219
PMCPMC9261292
OpenAlexW3189398664

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.