Evidence map›Paper›PMID 35813193›Full record

ReviewFrontiers in cell and developmental biology2022

Transformational Applications of Human Cardiac Organoids in Cardiovascular Diseases.

Wanling Xuan, Srinivas M Tipparaju, Muhammad Ashraf

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Hydrogels for Cardiac Tissue Regeneration: Current and Future Developments.International journal of molecular sciences · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Development of Novel 3D Spheroids for Discrete Subaortic Stenosis.Cardiovascular engineering and technology · 2024
    Article
  7. Bioprinting of Cardiac Tissue in Space: Where Are We?Advanced healthcare materials · 2023
    Article
  8. Recent Advances in Generation of In Vitro Cardiac Organoids.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Wanling XuanDepartment of Pharmaceutical Sciences, USF Health Taneja College of Pharmacy, University of South Florida, Tampa, FL, United States.
Srinivas M TipparajuDepartment of Pharmaceutical Sciences, USF Health Taneja College of Pharmacy, University of South Florida, Tampa, FL, United States.
Muhammad AshrafVascular Biology Center, Medical College of Georgia, Augusta University, Augusta, GA, United States.
University of South Florida · USAugusta University · US

Funding

Innovative Approaches to Treat Duchenne Muscular Dystrophy Using iPSC-Derived Muscle ProgenitorsR01AR070029 · NIAMS · AUGUSTA UNIVERSITY · PI ASHRAF, MUHAMMAD, TANG, YAO LIANG · 2016 to 2021
$2.6M
Notch1/miR-322 Axis in Stem Cell Mediated Vascular RepairR01HL134354 · NHLBI · AUGUSTA UNIVERSITY · PI ASHRAF, MUHAMMAD, TANG, YAO LIANG · 2016 to 2020
$2.5M
Protecting the Diabetic Skeletal Muscle by Nampt ActivationR01DK119066 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI BROTTO, MARCO, TIPPARAJU, SRINIVAS M. · 2019 to 2023
$2.0M
hiPS cells derived skeletal muscle progenitors and their extracellular vesicles for treatment of sarcopeniaR01AG070145 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI XUAN, WANLING · 2021 to 2025
$1.8M
NHLBI NIH HHS R01 HL134354NIA NIH HHS R01 AG070145NIDDK NIH HHS R01 DK119066
6 · The paper itself

Abstract

Organoid technology has significantly advanced in recent years and revolutionized the field for generation of organs using

Indexed as

heartiPSCorganoidsstem cellstissue culture

Identifiers

PMID35813193
PMCPMC9261984
OpenAlexW4281994923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.