Evidence map›Paper›PMID 35812987›Full record

ArticleJournal of the Society for Cardiovascular Angiography & Interventions

Sex Differences in Clinical Characteristics, Management Strategies, and Outcomes of STEMI With COVID-19: NACMI Registry.

Odayme Quesada, Logan Van Hon, Mehmet Yildiz, Mina Madan, Cristina Sanina, Laura Davidson, Wah Wah Htun, Jacqueline Saw, Santiago Garcia, Payam Dehghani and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the Society for Cardiovascular Angiography & Interventions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. The impact of the coronavirus pandemic on patients hospitalized due to acute coronary syndrome.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2023
    Review
  4. Article
  5. Article
  6. Review
  7. Sex Differences in Acute Coronary Syndromes: A Global Perspective.Journal of cardiovascular development and disease · 2022
    Review
  8. STEMIs and a Closer Look at MINOCA During the COVID-19 Pandemic.Journal of the Society for Cardiovascular Angiography & Interventions
    Article
  9. Journal of the Society for Cardiovascular Angiography & Interventions
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 2 countries.

Odayme QuesadaWomen's Heart Center, The Christ Hospital Heart and Vascular Institute, Cincinnati, Ohio.
Logan Van HonEssentia Health, Duluth, Minnesota.
Mehmet YildizThe Carl and Edyth Lindner Center for Research and Education, The Christ Hospital, Cincinnati, Ohio.
Mina MadanSchulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Cristina SaninaMontefiore Medical Center, Bronx, New York.
Laura DavidsonNorthwestern University Feinberg School of Medicine, Chicago, Illinois.
Wah Wah HtunGundersen Health System, La Crosse, Wisconsin.
Jacqueline SawVancouver General Hospital, Vancouver, British Columbia, Canada.
Santiago GarciaThe Carl and Edyth Lindner Center for Research and Education, The Christ Hospital, Cincinnati, Ohio.
Payam DehghaniPrairie Vascular Research Inc, Regina, Saskatchewan, Canada.
Larissa StanberryMinneapolis Heart Institute Foundation, Minneapolis, Minnesota.
Anna BortnickMontefiore Medical Center, Bronx, New York.
Timothy D HenryThe Carl and Edyth Lindner Center for Research and Education, The Christ Hospital, Cincinnati, Ohio.
Cindy L GrinesNorthside Cardiovascular Institute, Atlanta, Georgia.
Catherine BenzigerEssentia Health, Duluth, Minnesota.
Christ Hospital · USEssentia Health · USMontefiore Medical Center · USChrist Hospital · USGenome Prairie · CAGundersen Health System · USMinneapolis Heart Institute Foundation · USNorthside Hospital · USNorthwestern University · USSunnybrook Health Science Centre · CAVancouver General Hospital · CA

Funding

Hypertensive Disorders of Pregnancy: Pathways to Future Cardiovascular DiseaseK23HL151867 · NHLBI · THE CHRIST HOSPITAL · PI QUESADA, ODAYME · 2020 to 2024
$799k
NHLBI NIH HHS K23 HL151867
6 · The paper itself

Abstract

Background: Women with ST-segment elevation myocardial infarction (STEMI) had worse outcomes than men prior to the COVID-19 pandemic. Although concomitant COVID-19 infection increases mortality risk in STEMI patients, no studies have evaluated sex differences in this context. Methods: The North American COVID-19 STEMI registry is a prospective, multicenter registry of hospitalized STEMI patients with COVID-19 infection. We compared sex differences in clinical characteristics, presentation, management strategies, and in-hospital mortality. Results: Among 585 patients with STEMI and COVID-19 infection, 154 (26.3%) were women. Compared to men, women were significantly older, had a higher prevalence of diabetes and stroke/transient ischemic attack, and were more likely to be on statins on presentation. Men more frequently presented with chest pain, whereas women presented with dyspnea. Women more often had STEMI without an identified culprit lesion than men (33% vs 18%, Conclusions: In patients presenting with STEMI in the context of COVID-19, the in-hospital mortality rate was 30% and similar for men and women. Lack of an identifiable culprit lesion was common in the setting of COVID-19 for both sexes but more likely in women (1/3 of women vs 1/5 of men). Evaluation of specific underlying etiologies is underway to better define the full impact of COVID-19 on STEMI outcomes and better understand the observed sex differences.

Indexed as

COVID-19MI, myocardial infarctionMINOCA, myocardial infarction with nonobstructive coronary artery diseasemortalityNACMI, North American COVID-19 ST-Segment Elevation Myocardial InfarctionPCI, percutaneous coronary interventionsex differencesSTEMISTEMI, ST-segment elevation myocardial infarctionTIA, transient ischemic attack

Identifiers

PMID35812987
PMCPMC9117757
OpenAlexW4280506903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.