Evidence map›Paper›PMID 35812732›Full record

ArticleFrontiers in genetics2022

Upregulated miRNAs on the

Jenilson da Silva, Carla Cutrim da Costa, Ingryd de Farias Ramos, Ana Carolina Laus, Luciane Sussuchi, Rui Manuel Reis, André Salim Khayat, Luciane Regina Cavalli, Silma Regina Pereira

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jenilson da SilvaPostgraduate Program in Health Science, Federal University of Maranhão, São Luís, Brazil.
Carla Cutrim da CostaDegree in Biological Sciences, Department of Biology, Federal University of Maranhão, São Luís, Brazil.
Ingryd de Farias RamosPostgraduate Program in Oncology and Medical Sciences, Federal University of Pará, Belém, Brazil.
Ana Carolina LausMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.
Luciane SussuchiMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.
Rui Manuel ReisMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.
André Salim KhayatOncology Research Center, Federal University of Pará, Belém, Brazil.
Luciane Regina CavalliResearch Institute Pelé Pequeno Príncipe, Faculdades Pequeno Príncipe, Curitiba, Brazil.
Silma Regina PereiraLaboratory of Genetics and Molecular Biology, Department of Biology, Federal University of Maranhão, São Luís, Brazil.
Hospital de Câncer de Barretos · BRUniversidade Federal do Maranhão · BRUniversidade Federal do Pará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer development by the human papillomavirus (HPV) infection can occur through the canonical HPV/p53/RB1 pathway mediated by the E2/E6/E7 viral oncoproteins. During the transformation process, HPV inserts its genetic material into host Integration Sites (IS), affecting coding genes and miRNAs. In penile cancer (PeCa) there is limited data on the miRNAs that regulate mRNA targets associated with HPV, such as the

Indexed as

HPVmiRNApenile cancerRb1TP53tumor suppressor repression

Identifiers

PMID35812732
PMCPMC9263206
OpenAlexW4283392673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.