Evidence map›Paper›PMID 35812690›Full record

ArticleWorld journal of clinical cases2022

Effectiveness and safety of chemotherapy for patients with malignant gastrointestinal obstruction: A Japanese population-based cohort study.

Gota Fujisawa, Ryota Niikura, Takuya Kawahara, Tetsuro Honda, Kenkei Hasatani, Naohiro Yoshida, Tsutomu Nishida, Tetsuya Sumiyoshi, Shu Kiyotoki, Takashi Ikeya and 4 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Gota FujisawaDepartment of Gastroenterology, Graduate school of Medicine, The University of Tokyo, Tokyo 1138655, Japan.
Ryota NiikuraGastroenterological Endoscopy, Tokyo Medical University, Tokyo 1600023, Japan. rniikura@triton.ocn.ne.jp.
Takuya KawaharaClinical Research Support Center, The University of Tokyo Hospital, Tokyo 1138655, Japan.
Tetsuro HondaDepartment of Gastroenterology, Nagasaki Harbor Medical Center, Nagasaki 8508555, Japan.
Kenkei HasataniDepartment of Gastroenterology, Fukui Prefectural Hospital, Fukui 9108526, Japan.
Naohiro YoshidaDepartment of Gastroenterology, Ishikawa Prefectural Central Hospital, Ishikawa 9208530, Japan.
Tsutomu NishidaDepartment of Gastroenterology, Toyonaka Municipal Hospital, Osaka 5608565, Japan.
Tetsuya SumiyoshiDepartment of Gastroenterology, Tonan Hospital, Hokkaido 0600004, Japan.
Shu KiyotokiDepartment of Gastroenterology, Shuto General Hospital, Yamaguchi 7420032, Japan.
Takashi IkeyaDepartment of Gastroenterology, St. Luke's International Hospital, Tokyo 1048560, Japan.
Masahiro AraiDepartment of Gastroenterology, Nerima Hikarigaoka Hospital, Tokyo 1790072, Japan.
Yoku HayakawaDepartment of Gastroenterology, Graduate school of Medicine, The University of Tokyo, Tokyo 1138655, Japan.
Takashi KawaiGastroenterological Endoscopy, Tokyo Medical University, Tokyo 1600023, Japan.
Mitsuhiro FujishiroDepartment of Gastroenterology, Graduate school of Medicine, The University of Tokyo, Tokyo 1138655, Japan.
Fukui Prefectural Hospital · JPIshikawa Prefectural Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impacts of chemotherapy on patients with malignant gastrointestinal obstructions remain unclear, and multicenter evidence is lacking.

aimTo evaluate the effectiveness and safety of chemotherapy in patients with unresectable malignant gastrointestinal obstructions.

methodsWe conducted a multicenter retrospective cohort study that compared the chemotherapy group who received any chemotherapeutics after interventions, including palliative surgery or self-expandable metal stent placement, for unresectable malignant gastrointestinal obstruction

resultsIn total, 470 patients in the chemotherapy group and 652 patients in the BSC group were analyzed. During the follow-up period of 54.1 mo, the median overall survival durations were 19.3 mo in the chemotherapy group and 5.4 mo in the BSC group (log-rank test,

conclusionChemotherapy after interventions for unresectable malignant gastrointestinal obstruction was associated with increased overall survival and patency duration.

Indexed as

ChemotherapyGastrointestinal cancerMalignant gastrointestinal obstructionPalliative surgerySelf-expandable metal stent

Identifiers

PMID35812690
PMCPMC9210883
OpenAlexW4281769933

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.