Evidence map›Paper›PMID 35812473›Full record

ArticleFrontiers in public health2022

The Association Between 2, 4-Dichlorophenoxyacetic Acid and Erectile Dysfunction.

Wei Wang, Yucheng Ma, Jiawei Chen, Liao Peng, Xiaoshuai Gao, Lede Lin, Fuxun Zhang, Yang Xiong, Feng Qin, Jiuhong Yuan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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  6. Dietary intakes of vitamin BTranslational andrology and urology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Wei WangAndrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.
Yucheng MaDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
Jiawei ChenDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
Liao PengDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
Xiaoshuai GaoDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
Lede LinDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
Fuxun ZhangAndrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.
Yang XiongAndrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.
Feng QinAndrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.
Jiuhong YuanAndrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: 2, 4-dichlorophenoxyacetic acid (2,4-D) is one of the most frequently used herbicides in the world, and it has been linked with low testosterone; however, studies regarding its effect on erectile function are limited. The current study aimed to determine the association between the 2,4-D exposure and erectile dysfunction (ED) in men from the National Health and Nutrition Examination Survey (NHANES). Methods: We analyzed data for urinary 2,4-D levels from 1,311 men (>20 years of age) in the NHANES 2001-2004. ED was assessed by a single, validated survey question. Multivariable logistic regression analysis utilizing sampling weights was performed to determine the relationship between 2,4-D exposure and ED. Results: Multivariable logistic regression models demonstrated no statistically significant association between 2,4-D exposure and ED after full adjustment [odds ratio (OR) 1.02; 95% CI 0.77-1.36; Conclusion: We demonstrated that there was no association between 2,4-D exposure and ED. Further studies are warranted to corroborate our results.

Indexed as

Erectile DysfunctionHerbicides2,4-Dichlorophenoxyacetic AcidCross-Sectional StudiesHumansMaleNutrition SurveysRisk Factors2,4-Dichlorophenoxyacetic AcidHerbicides24-dichlorophenoxyacetic aciderectile dysfunctionherbicidesmen's healthNHANES

Identifiers

PMID35812473
PMCPMC9263508
OpenAlexW4283382389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.