Evidence map›Paper›PMID 35812454›Full record

ArticleFrontiers in immunology2022

Tumor-Infiltrated CD8+ T Cell 10-Gene Signature Related to Clear Cell Renal Cell Carcinoma Prognosis.

Jie Wang, Feifan Huang, Jingjie Zhao, Peng Huang, Junhua Tan, Meiying Huang, Ruiying Ma, Yu Xiao, Siyuan He, Zechen Wang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jie WangCenter for Systemic Inflammation Research (CSIR), Youjiang Medical University for Nationalities, Baise, China.
Feifan HuangDepartment of Kidney Diseases, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Jingjie ZhaoLife Science and Clinical Research Center, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Peng HuangDepartment of Kidney Diseases, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Junhua TanDepartment of Kidney Diseases, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Meiying HuangDepartment of Kidney Diseases, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Ruiying MaDepartment of Kidney Diseases, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Yu XiaoDepartment of Kidney Diseases, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Siyuan HeCenter for Systemic Inflammation Research (CSIR), Youjiang Medical University for Nationalities, Baise, China.
Zechen WangCenter for Systemic Inflammation Research (CSIR), Youjiang Medical University for Nationalities, Baise, China.
Jiajia ShenCenter for Systemic Inflammation Research (CSIR), Youjiang Medical University for Nationalities, Baise, China.
Heming LuDepartment of Radiation Oncology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Lingzhang MengCenter for Systemic Inflammation Research (CSIR), Youjiang Medical University for Nationalities, Baise, China.
Affiliated Hospital of Youjiang Medical University for Nationalities · CNThe People's Hospital of Guangxi Zhuang Autonomous Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clear cell renal cell carcinoma (ccRCC) usually affects multiple organs (e.g., bone and brain), and patient prognosis is usually poor. Although it is known that CD8+ T cell infiltration can potentially alleviate ccRCC progression, few studies have concentrated on the correlation between CD8+ T cell infiltration and ccRCC prognosis. In this study, ten genes expressed by infiltrated CD8+ T cells (i.e.,

Indexed as

Carcinoma, Renal CellKidney NeoplasmsBiomarkersCD8-Positive T-LymphocytesHumansPrognosisProtein Tyrosine PhosphatasesBiomarkersProtein Tyrosine PhosphatasesPTP4A2 protein, humanCD8+ T cellclear cell renal cell carcinomaneutrophil metabolismpapillary renal cell carcinomascRNA-seq

Identifiers

PMID35812454
PMCPMC9263606
OpenAlexW4283449625

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.