Evidence map›Paper›PMID 35812399›Full record

ArticleFrontiers in immunology2022

Case Report: Novel STIM1 Gain-of-Function Mutation in a Patient With TAM/STRMK and Immunological Involvement.

Eduardo de la Fuente-Munoz, Ana Van Den Rym, Blanca García-Solis, Juliana Ochoa Grullón, Kissy Guevara-Hoyer, Miguel Fernández-Arquero, Lucía Galán Dávila, Jorge Matías-Guiú, Silvia Sánchez-Ramón, Rebeca Pérez de Diego

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Mosaic STIM1 variant associated with epidermal naevus.The British journal of dermatology · 2026
    Article
  2. Review
  3. Review
  4. STIM1 and lipid interactions at ER-PM contact sites.American journal of physiology. Cell physiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Eduardo de la Fuente-MunozClinical Immunology Department, San Carlos Clinical Hospital, Madrid, Spain.
Ana Van Den RymLaboratory of Immunogenetics of Human Diseases, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid, Spain.
Blanca García-SolisLaboratory of Immunogenetics of Human Diseases, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid, Spain.
Juliana Ochoa GrullónClinical Immunology Department, San Carlos Clinical Hospital, Madrid, Spain.
Kissy Guevara-HoyerClinical Immunology Department, San Carlos Clinical Hospital, Madrid, Spain.
Miguel Fernández-ArqueroClinical Immunology Department, San Carlos Clinical Hospital, Madrid, Spain.
Lucía Galán DávilaNeurology Department, San Carlos Clinical Hospital, Madrid, Spain.
Jorge Matías-GuiúNeurology Department, San Carlos Clinical Hospital, Madrid, Spain.
Silvia Sánchez-RamónClinical Immunology Department, San Carlos Clinical Hospital, Madrid, Spain.
Rebeca Pérez de DiegoLaboratory of Immunogenetics of Human Diseases, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid, Spain.
Hospital Clínico San Carlos · ESHospital La Paz Institute for Health Research · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gain-of-function (GOF) mutations in

Indexed as

DyslexiaIchthyosisMyopathies, Structural, CongenitalBlood Platelet DisordersCalciumChildErythrocytes, AbnormalGain of Function MutationHumansMigraine DisordersMiosisMuscle FatigueMutationNeoplasm ProteinsSpleenStromal Interaction Molecule 1CalciumNeoplasm ProteinsSTIM1 protein, humanStromal Interaction Molecule 1calcium signallinggain of functioninfectionmyopathySTIM1

Identifiers

PMID35812399
PMCPMC9263075
OpenAlexW4283371342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.