Evidence map›Paper›PMID 35812361›Full record

ArticleFaculty reviews2022

Restoring partial vision to a blind patient.

Larry I Benowitz, John E Dowling, Roman J Giger, Thomas V Johnson, Donald J Zack

Open access · diamondAbstract readComment
In one paragraph

Article in Faculty reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Larry I BenowitzBoston Children's Hospital, Harvard Medical School.ORCID https://orcid.org/0000-0002-0277-7222
John E DowlingHarvard University.
Roman J GigerUniversity of Michigan Medical School.ORCID https://orcid.org/0000-0002-2926-3336
Thomas V JohnsonWilmer Eye Institute, Johns Hopkins University School of Medicine.ORCID https://orcid.org/0000-0002-5372-5457
Donald J ZackJohns Hopkins University School of Medicine.ORCID https://orcid.org/0000-0002-7966-1973
Johns Hopkins University · USBoston Children's Hospital · USHarvard University Press · USUniversity of Michigan · US

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4M
Transplantation of human stem cell-derived neurons for retinal ganglion cell replacement and optic nerve regeneration.K08EY031801 · NEI · JOHNS HOPKINS UNIVERSITY · PI JOHNSON, THOMAS VINCENT · 2020 to 2024
$945k
NEI NIH HHS K08 EY031801NICHD NIH HHS P50 HD105351
6 · The paper itself

Abstract

This paper reports an important breakthrough in partially restoring sight to a man who had lost his vision due to retinitis pigmentosa (RP), a heritable retinal degenerative disease that affects approximately 1 in 4000 people. Long considered an insurmountable challenge, a stellar team of vision scientists, engineers, basic biologists, and others, working together for many years, has enabled a man who had been legally blind for decades to begin distinguishing objects and navigating his environment

Indexed as

conesretinal ganglion cellsRetinitis pigmentosaRGCrods

Identifiers

PMID35812361
PMCPMC9239363
OpenAlexW4285048567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.