Evidence map›Paper›PMID 35812237›Full record

ArticleFrontiers in neuroscience2022

The Effectiveness of Targeted Electrical Stimulation

Walter Di Nardo, Tiziana Di Cesare, Angelo Tizio, Gaetano Paludetti, Anna Rita Fetoni

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Walter Di NardoDipartimento di Scienze dell'Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, UOC di Otorinolaringoiatria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Tiziana Di CesareDipartimento di Scienze dell'Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, UOC di Otorinolaringoiatria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Angelo TizioDipartimento di Scienze dell'Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, UOC di Otorinolaringoiatria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Gaetano PaludettiDipartimento di Scienze dell'Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, UOC di Otorinolaringoiatria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Anna Rita FetoniDipartimento di Neuroscienze, Sezione di Audiologia, Universitá Federico II, Naples, Italy.
Agostino Gemelli University Polyclinic · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The cause of tinnitus improvement in cochlear implant (CI) users is not understood. On the basis that a spatially limited dysfunction in the auditory pathway could cause tinnitus, we used single-channel stimulation to evaluate any variation of tinnitus-perceived loudness and identify the cochlear regions involved. Materials and Methods: It was an observational prospective case-crossover study. After the first mapping, 21 adults with unilateral CI and chronic tinnitus expressed their tinnitus loudness based on the Visual Analog Scale (VAS) score (0-10) at baseline (L Results: We observed a significant reduction of tinnitus loudness during the experimental procedure [L Conclusion: Targeted intracochlear electrical stimulation improved chronic tinnitus perception, especially in monotone tinnitus, and the apical region was mainly involved. Our results provide new insights into the pathophysiological mechanisms of tinnitus and targets for innovative therapeutic strategies.

Indexed as

cochlear implantcochlear regionsintracochlear electrical stimulationpitch matchtinnitus

Identifiers

PMID35812237
PMCPMC9263381
OpenAlexW4283454420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.