Evidence map›Paper›PMID 35812091›Full record

ArticleFrontiers in neurology2022

Low 25-Hydroxyvitamin D Levels Are Associated With Residual Dizziness After Successful Treatment of Benign Paroxysmal Positional Vertigo.

Yunqin Wu, Kun Han, Weiwei Han, Zhenyi Fan, Min Zhou, Xiaoxiong Lu, Xiaoxia Liu, Li Li, Liwen Du

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Randomized Controlled Trial Assessing Vitamin D's Role in Reducing BPPV Recurrence in Older Adults.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yunqin WuDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Kun HanDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Weiwei HanDepartment of Rehabilitation, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Zhenyi FanDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Min ZhouDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Xiaoxiong LuDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Xiaoxia LiuDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Li LiDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.
Liwen DuDepartment of Emergency, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Vitamin D (Vit D) regulates calcium and phosphate metabolism and helps to maintain otolith organ function. Residual dizziness (RD) is one of the most common complications after the successful treatment of benign paroxysmal positional vertigo (BPPV). Various theories have been suggested to explain the cause of RD, and otolith organ disorder is the most evident cause of RD. This study aimed to investigate the association between serum levels of Vit D and the occurrence of RD after the successful treatment of BPPV. Methods: A prospective study including patients who were diagnosed with de novo posterior semicircular canal-type BPPV (PC-BPPV) was conducted at our institution from May 2017 to May 2019. All the patients underwent canalith repositioning procedures and were followed up. Univariate and multivariate analyses were performed to investigate the relationship between serum 25-hydroxy vitamin D (25(OH)D) levels and RD occurrence after successful BPPV treatment. Results: In total, 123 patients with PC-BPPV were enrolled, and 41.5% (51/123) experienced RD. The serum level of 25(OH)D was significantly lower in PC-BPPV patients with RD [median 16.2 ng/ml (IQR 12.9-22.1)] than in patients without RD [median 20.5 ng/ml (IQR 16.5-26.5)] ( Conclusion: Low 25(OH)D levels are associated with the development of RD in patients with PC-BPPV after successful treatment. Further efforts to validate and elucidate the mechanism are needed.

Indexed as

25-hydroxy vitamin Dbenign paroxysmal positional vertigocanalith repositioning procedureresidual dizzinessrisk factor

Identifiers

PMID35812091
PMCPMC9256914
OpenAlexW4283374105

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.