Evidence map›Paper›PMID 35812034›Full record

ArticleFrontline gastroenterology2022

Palliative long-term abdominal drains for the management of refractory ascites due to cirrhosis: a consensus document.

Lucia Macken, Margaret Corrigan, Wendy Prentice, Fiona Finlay, Joanne McDonagh, Neil Rajoriya, Claire Salmon, Mhairi Donnelly, Catherine Evans, Bhaskar Ganai and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Frontline gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Guideline
  2. [Guidelines on the management of ascites in cirrhosis (2023 version)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
    Guideline
  3. Article
  4. Review
  5. Article
  6. Home Management of Refractory Ascites in Decompensated Cirrhosis With Long-Term Abdominal Drains, a Pilot Study.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
  7. Review
  8. Palliative long-term abdominal drainsWorld journal of hepatology · 2024
    Article
  9. Article
  10. Update in the Treatment of the Complications of Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Review
  11. Diagnostic and therapeutic abdominal paracentesis.The Medical journal of Australia · 2023
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 1 country.

Lucia MackenGastroenterology and Hepatology, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.
Margaret CorriganHepatology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Wendy PrenticeDepartment of Palliative Care Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Fiona FinlayPalliative Medicine, Queen Elizabeth University Hospital Campus, Glasgow, UK.ORCID 0000-0001-8549-9231
Joanne McDonaghLiver Unit, Queen Elizabeth Hospital, Birmingham, UK.
Neil RajoriyaLiver Unit, Queen Elizabeth Hospital, Birmingham, UK.ORCID 0000-0003-3892-2206
Claire SalmonHepatology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Mhairi DonnellyLiver Unit, Freeman Hospital, Newcastle upon Tyne, UK.ORCID 0000-0001-7655-7284
Catherine EvansKing's College London, London, UK.
Bhaskar GanaiGastroenterology and Hepatology, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.
Joan BedlingtonLIVErNORTH, Newcastle, UK.
Shani SteerPatient and Public involvement, Brighton, UK.
Mark WrightHepatology, University Hospital Southampton, Southampton, UK.ORCID 0000-0001-7046-241X
Ben HudsonHepatology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.
Sumita VermaGastroenterology and Hepatology, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.ORCID 0000-0001-7021-8409
British Association for the Study of the Liver/British Society of Gastroenterology (BASL/BSG) End of Life Special Interest Group
Queen Elizabeth Hospital Birmingham · GBUniversity Hospitals Sussex NHS Foundation Trust · GBBrighton and Sussex Medical School · GBFreeman Hospital · GBKing's College Hospital NHS Foundation Trust · GBKing's College London · GBQueen Elizabeth University Hospital · GBRoyal Devon & Exeter NHS Foundation Trust · GBSheffield Teaching Hospitals NHS Foundation Trust · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Palliative care remains suboptimal in advanced cirrhosis, in part relating to a lack of evidence-based interventions. Ascites remains the most common cirrhosis complication resulting in hospitalisation. Many patients with refractory ascites are not candidates for liver transplantation or transjugular intrahepatic portosystemic shunt, and therefore, require recurrent palliative large volume paracentesis in hospital. We review the available evidence on use of palliative long-term abdominal drains in cirrhosis. Pending results of a national trial (REDUCe 2) and consistent with recently published national and American guidance, long-term abdominal drains cannot be regarded as standard of care in advanced cirrhosis. They should instead be considered only on a case-by-case basis, pending definitive evidence. This manuscript provides consensus to help standardise use of long-term abdominal drains in cirrhosis including patient selection and community management. Our ultimate aim remains to improve palliative care for this under researched and vulnerable cohort.

Indexed as

ASCITESCLINICAL TRIALSLIVER CIRRHOSISPERITONITIS

Identifiers

PMID35812034
PMCPMC9234735
OpenAlexW4281714795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.