Evidence map›Paper›PMID 35811933›Full record

ArticleACS omega2022

Impact of Composition and Morphology of Ketoconazole-Loaded Solid Lipid Nanoparticles on Intestinal Permeation and Gastroplus-Based Prediction Studies.

Shaya Jubran Aljurbui, Afzal Hussain, Mohammad Yusuf, Mohhammad Ramzan, Obaid Afzal, Basmah Almohaywi, Sabina Yasmin, Abdulmalik Saleh Alfawaz Altamimi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Shaya Jubran AljurbuiDepartment of Pharmacy, Riyadh Military Hospital, P.O. Box 7897, Riyadh 11159, Saudi Arabia.
Afzal HussainDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Mohammad YusufDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Mohhammad RamzanDepartment of Pharmaceutics, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, Punjab 160014, India.ORCID https://orcid.org/0000-0001-9029-9752
Obaid AfzalDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
Basmah AlmohaywiDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University (KKU), Abha 61421, Saudi Arabia.
Sabina YasminDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University (KKU), Abha 61421, Saudi Arabia.
Abdulmalik Saleh Alfawaz AltamimiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
King Khalid University · SAPrince Sattam Bin Abdulaziz University · SAKing Saud University · SAPanjab University · INRiyadh Armed Forces Hospital · SATaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ketoconazole (KTZ) is a potential oral antifungal agent to control systemic and local infections. This study addresses the impact of composition (tween 80 and compritol as CATO) and morphology on permeation (stomach, jejunum, and ileum) profiles of KTZ-loaded solid lipid nanoparticles (SLNs) in rats followed by

Identifiers

PMID35811933
PMCPMC9260901
OpenAlexW4283166065

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.