Evidence map›Paper›PMID 35811872›Full record

ArticleACS omega2022

Facile Solid-Phase Synthesis of Well-Defined Defect Lysine Dendrimers.

Yong Liao, Yuan-Ting Chan, Vijayasimha Molakaseema, Anand Selvaraj, Hui-Ting Chen, Yun-Ming Wang, Yeun-Mun Choo, Chai-Lin Kao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Solid-Phase Synthesis of Well-Defined Defect Lysine Dendrimers.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Yong LiaoDepartment of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Yuan-Ting ChanDepartment of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Vijayasimha MolakaseemaDepartment of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Anand SelvarajDepartment of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Hui-Ting ChenDepartment of Pharmacy, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Yun-Ming WangDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan.
Yeun-Mun ChooDepartment of Chemistry, University of Malaya, Kuala Lumpur 50603, Malaysia.ORCID https://orcid.org/0000-0001-9891-5898
Chai-Lin KaoDepartment of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID https://orcid.org/0000-0003-3991-9092
Kaohsiung Medical University · TWNational Yang Ming Chiao Tung University · TWNational Sun Yat-sen University · TWUniversity of Malaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An efficient solid-phase method has been reported to prepare well-defined lysine defect dendrimers. Using orthogonally protected lysine residues, pure G2 to G4 lysine defect dendrimers were prepared with 48-95% yields within 13 h. Remarkably, high-purity products were collected via precipitation without further purification steps. This method was applied to prepare a pair of 4-carboxyphenylboronic acid-decorated defect dendrimers (

Identifiers

PMID35811872
PMCPMC9260950
OpenAlexW4283024081

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.