Evidence map›Paper›PMID 35811813›Full record

ArticlePeerJ2022

Fatou Thiam, Gora Diop, Cedric Coulonges, Céline Derbois, Babacar Mbengue, Alassane Thiam, Cheikh Momar Nguer, Jean Francois Zagury, Jean-Francois Deleuze, Alioune Dieye

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Human genetic variations conferring resistance to malaria.Journal of translational medicine · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Fatou Thiam *Groupe de Recherche Biotechnologie Appliquée et Bioprocédés Environnementaux (GRBA-BE), Laboratoire Eau, Energie, Environnement et Procédés Industriels (LE3PI), Département de Génie Chimique et Biologie Appliquée, Ecole Supérieure Polytechnique, Université Cheikh Anta DIOP de Dakar, Dakar Fann, Dakar, Sénégal.
Gora Diop *Unité Postulante de Biologie Génétique, Génomique et Bio-informatique (G2B), Département de Biologie Animale, Faculté des Sciences et Techniques, Université Cheikh Anta DIOP, Avenue Cheikh Anta DIOP, Dakar Fann, Dakar, Sénégal.
Cedric CoulongesEquipe GBA «Génomique, Bioinformatique & Applications », Conservatoire National des Arts et Métiers, Paris, France.
Céline DerboisCEA, Centre National de Recherche en Génomique Humaine, Université Paris-Saclay, Evry, France.
Babacar MbengueService d'Immunologie, Faculté de Médecine, de Pharmacie et d'Odontostomatologie, Université Cheikh Anta DIOP, Dakar, Sénégal.
Alassane ThiamPole d'Immunophysiopathologie & Maladies Infectieuses (IMI), Institut Pasteur de Dakar, Dakar, Sénégal.
Cheikh Momar NguerGroupe de Recherche Biotechnologie Appliquée et Bioprocédés Environnementaux (GRBA-BE), Laboratoire Eau, Energie, Environnement et Procédés Industriels (LE3PI), Département de Génie Chimique et Biologie Appliquée, Ecole Supérieure Polytechnique, Université Cheikh Anta DIOP de Dakar, Dakar Fann, Dakar, Sénégal.
Jean Francois ZaguryEquipe GBA «Génomique, Bioinformatique & Applications », Conservatoire National des Arts et Métiers, Paris, France.
Jean-Francois DeleuzeCEA, Centre National de Recherche en Génomique Humaine, Université Paris-Saclay, Evry, France.
Alioune DieyeService d'Immunologie, Faculté de Médecine, de Pharmacie et d'Odontostomatologie, Université Cheikh Anta DIOP, Dakar, Sénégal.
Cheikh Anta Diop University · SNConservatoire National des Arts et Métiers · FRCEA Paris-Saclay · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRInstitut Pasteur de Dakar · SN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Host genetic factors contribute to the variability of malaria phenotypes and can allow a better understanding of mechanisms involved in susceptibility and/or resistance to Methods: We performed a retrospective study with 437 samples, 323 patients recruited in hospitals located in three different endemic areas where malaria episodes were confirmed and 114 free malaria controls. The patients enrolled were classified into two groups: severe malaria (SM) (153 patients) and uncomplicated malaria (UM) (170 patients). PCR and DNA sequencing assessed host genetic polymorphisms in Results: Six frequent SNPs with minor allele frequencies (MAF) > 3% were detected in the Conclusion: Our data report

Indexed as

MalariaMalaria, FalciparumGlucosephosphate DehydrogenaseHemoglobin SubunitsHumansMaliPolymorphism, Single NucleotidePrevalenceRetrospective StudiesG6PD protein, humanGlucosephosphate DehydrogenaseHemoglobin SubunitsG6PDHBBPolymorphismsSenegalSevere malaria

Identifiers

PMID35811813
PMCPMC9266585
OpenAlexW4283804025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.