ArticleFrontiers in cardiovascular medicine2022
Global Trends in Mortality and Burden of Stroke Attributable to Lead Exposure From 1990 to 2019.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Prediction models for post-thrombectomy brain edema in patients with acute ischemic stroke: a systematic review and meta-analysis.Frontiers in neurology · 2023Pooled it
- Exposure to lead and incidence of Alzheimer's disease and all-cause dementia in the United States.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Environment and CVD: moving from Risk Prediction to Risk Management.Current atherosclerosis reports · 2026Review
- The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.Frontiers in public health · 2025Article
- Impact of snoring on the risk of stroke in patients with diabetes mellitus.Sleep & breathing = Schlaf & Atmung · 2024Article
- Chronic lead exposure and burden of cardiovascular disease during 1990-2019: a systematic analysis of the global burden of disease study.Frontiers in cardiovascular medicine · 2024Article
- Trends in urine lead and associated mortality in US adults: NHANES 1999-2018.Frontiers in nutrition · 2024Article
- Association of Blood Heavy Metal Exposure with Atherosclerotic Cardiovascular Disease (ASCVD) Among White Adults: Evidence from NHANES 1999-2018.Biological trace element research · 2023Article
- Trends in predicted 10-year risk for cardiovascular diseases among patients with type 2 diabetes in Thailand, from 2014 to 2018.BMC cardiovascular disorders · 2023Article
- Disturbed Ratios between Essential and Toxic Trace Elements as Potential Biomarkers of Acute Ischemic Stroke.Nutrients · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Lead exposure is an important risk factor for stroke. However, the latest global spatiotemporal patterns of lead exposure-related stroke burden were unclear. In this study, we assessed this topic. Methods: The data were obtained from the Global Burden of Disease Study (2019). The estimated annual percentage change (EAPC) was estimated to evaluate the temporal trends of the age-standardized mortality and disability-adjusted life years (DALYs) rates (ASMR and ASDR) of stroke attributable to lead exposure. Results: In 2019, the numbers of global stroke deaths and DALYs attributable to lead exposure were 305.27 and 6738.78 thousand, respectively. The corresponding ASMR and ASDR were highest in males, the elderly population, low and middle-income countries, and the intracerebral hemorrhage subtype. From 1990 to 2019, the ASMR and ASDR of global stroke attributable to lead exposure decreased [ASMR: EAPC = -1.34, 95% confidence interval (CI): (-1.57, -1.10); ASDR: EAPC = -1.74, 95% CI: (-1.95, -1.52)], especially in females, the high-income countries, and the subarachnoid hemorrhage subtype. Conclusion: This study emphasizes the importance of continued implementation of lead exposure prevention strategies and improved high-efficiency treatment and stroke acute health care, especially in low and middle-income countries.
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