Evidence map›Paper›PMID 35811630›Full record

ArticleJournal of affective disorders reports2022

Antenatal depressive symptoms and behavioral outcomes in children at 78 months: A study from South India.

Susan Thomas, Tinku Thomas, Anura Kurpad, Christopher P Duggan, Krishnamachari Srinivasan

Open access · goldAbstract read
In one paragraph

Article in Journal of affective disorders reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Susan ThomasDivision of Mental Health and Neurosciences, St. John's Research Institute, St John's National Academy of Health Sciences, Bengaluru, Karnataka 560034, India.
Tinku ThomasDepartment of Biostatistics, St. John's Medical College, Bengaluru, Karnataka, India.
Anura KurpadDepartment of Physiology, St. John's Medical College, Bengaluru, Karnataka, India.
Christopher P DugganCenter for Nutrition, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston MA, USA.
Krishnamachari SrinivasanDivision of Mental Health and Neurosciences, St. John's Research Institute, St John's National Academy of Health Sciences, Bengaluru, Karnataka 560034, India.
St.John's Medical College Hospital · INSt. John's National Academy of Health Sciences · INBoston Children's Hospital · US

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
Patient-oriented Research in Pediatric Diarrheal DiseasesK24DK104676 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI DUGGAN, CHRISTOPHER P · 2015 to 2019
$903k
FIC NIH HHS D43 TW009343NIDDK NIH HHS K24 DK104676NIDDK NIH HHS P30 DK040561Wellcome Trust
6 · The paper itself

Abstract

Background: Low and middle income countries report a higher prevalence of antenatal depression. The association between antenatal depressive symptoms and behavioral outcomes in children at 78 months in motherchild dyads who participated in a randomized control trial of maternal B12 supplementation during pregnancy was examined in this study. Methods: Children of 140 women, out of 366 who had participated in the placebo-controlled, randomized trial of vitamin B12 supplementation during pregnancy and 6 weeks post-partum, on whom serial assessments of depressive symptoms in each of the trimesters were done using the Kessler's 10 Psychological Distress Scale (K10), were assessed using the Strength and Difficulties Questionnaire (SDQ) at 78 months. Results: Thirty seven women (26.4%) reported depressive symptoms at one trimester (intermittent group) and 28 women (20%) had depressive symptoms in at least 2 trimesters (persistent group). On adjusted bivariate regression analysis, children of women with intermittent antenatal depressive symptoms scored lower on the prosocial behavior subscale of SDQ compared to children of mothers with no depressive symptoms ( B=;-0.91, 95% CI: -1.65,-0.18; p=0.016). Limitations: The use of a screening measure to assess maternal depression, the assessment of the children's behavior based only on the mothers' reports and the small number of women with persistent depressive symptoms in our sample is important limitations. Conclusions: The possible association between antenatal depressive symptoms and prosocial behavior in children point to the need for routine assessment and intervention for emotional disorders during pregnancy.

Indexed as

Antenatal depressionchild behavior outcomesexternalizing symptomsinternalizing symptomsprosocial behaviour

Identifiers

PMID35811630
PMCPMC9261908
OpenAlexW4224279157

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.