Evidence map›Paper›PMID 35811395›Full record

ArticleHuman brain mapping2022

On predictability of individual functional connectivity networks from clinical characteristics.

Emily L Morris, Stephan F Taylor, Jian Kang

Abstract read
In one paragraph

Article in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily L MorrisDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-7357-0483
Stephan F TaylorDepartment of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA.
Jian KangDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.

Funding

Statistical ICA Methods for Analysis & Integration of Multi-dimensional Data Diversity SupplementR01MH105561 · NIMH · EMORY UNIVERSITY · PI GUO, YING, KANG, JIAN · 2014 to 2024
$4.3M
Scalable Bayesian methods for big imaging data analysisR01DA048993 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JOHNSON, TIMOTHY D, KANG, JIAN · 2020 to 2024
$1.6M
Bayesian Network Biomarker Selection in Metabolomics DataR01GM124061 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KANG, JIAN · 2017 to 2020
$1.4M
NIGMS NIH HHS R01 GM124061NIMH NIH HHS R01 MH105561
6 · The paper itself

Abstract

In recent years, understanding functional brain connectivity has become increasingly important as a scientific tool with potential clinical implications. Statistical methods, such as graphical models and network analysis, have been adopted to construct functional connectivity networks for single subjects. Here we focus on studying the association between functional connectivity networks and clinical characteristics such as psychiatric symptoms and diagnoses. Utilizing machine learning algorithms, we propose a method to examine predictability of functional connectivity networks from clinical characteristics. Our methods can identify salient clinical characteristics predictive of the whole brain network or specific subnetworks. We illustrate our methods on the analysis of fMRI data in the Philadelphia Neurodevelopmental Cohort study, demonstrating clinically meaningful results.

Indexed as

Brain MappingMagnetic Resonance ImagingAlgorithmsBrainCohort StudiesHumans

Identifiers

PMID35811395
PMCPMC9812246

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.