Evidence map›Paper›PMID 35811380›Full record

ArticlePsychogeriatrics : the official journal of the Japanese Psychogeriatric Society2022

The recognition and management of neuropsychiatric symptoms in early Alzheimer's disease: a qualitative study among Dutch memory clinic physicians.

Willem S Eikelboom, Najoua Lazaar, Rozemarijn L van Bruchem-Visser, Francesco U S Mattace-Raso, Michiel Coesmans, Rik Ossenkoppele, Esther van den Berg, Janne M Papma

Open access · hybridAbstract read
In one paragraph

Article in Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Willem S EikelboomDepartment of Neurology and Alzheimer Center Erasmus MC, Erasmus MC University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-5004-5141
Najoua LazaarDepartment of Neurology and Alzheimer Center Erasmus MC, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Rozemarijn L van Bruchem-VisserDepartment of Geriatrics and Alzheimer Center Erasmus MC, Erasmus MC University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-6833-7641
Francesco U S Mattace-RasoDepartment of Geriatrics and Alzheimer Center Erasmus MC, Erasmus MC University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-1688-6497
Michiel CoesmansDepartment of Psychiatry, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Rik OssenkoppeleDepartment of Neurology & Alzheimer Center Amsterdam, Amsterdam University Medical Centers, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0003-1584-7477
Esther van den BergDepartment of Neurology and Alzheimer Center Erasmus MC, Erasmus MC University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-8120-7366
Janne M PapmaDepartment of Neurology and Alzheimer Center Erasmus MC, Erasmus MC University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-2790-438X
Erasmus MC · NLLund University · SE

Funding

Alzheimer Nederland and Memorabel ZonMw 733050823
6 · The paper itself

Abstract

backgroundTimely recognition and treatment of neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) dementia may improve quality of life, reduce caregiver burden, and delay disease progression. However, management of NPS in early AD dementia remains challenging. To date, little is known about the specific challenges for memory clinic-based physicians. The aims of this qualitative study were to obtain insights regarding the recognition and treatment of NPS in AD dementia in the memory clinic, to identify challenges experienced by physicians while managing NPS, and to examine the attitudes of memory clinic physicians on the role of the memory clinic in the care for NPS in early AD dementia.

methodsSemi-structured interviews were conducted with 13 physicians working at a memory clinic in the Netherlands (n = 7 neurologist, n = 6 geriatrician, 46% female). The data were analyzed by two independent researchers using thematic analysis.

resultsWe observed large variation among Dutch memory clinic physicians regarding care practices, expertise, and attitudes on the role of the memory clinic considering NPS in AD dementia. The most prominent challenges that memory clinic physicians experienced while managing NPS included that the outpatient setting complicates the recognition and treatment of NPS, a lack of experience, knowledge, and/or resources to adequately apply non-pharmacological interventions, and a lack of consensus among physicians on the role of the memory clinic in NPS recognition and management.

conclusionsWe identified challenges that need to be addressed to improve the early recognition and adequate management of NPS in AD dementia at the memory clinic.

Indexed as

Alzheimer DiseasePhysiciansDisease ProgressionFemaleHumansMaleQualitative ResearchQuality of LifeAlzheimer's diseasebehavioural symptomsdementianeuropsychiatric symptomsqualitative research

Identifiers

PMID35811380
PMCPMC9541792
OpenAlexW4285009596

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.