Evidence map›Paper›PMID 35811327›Full record

ArticlePediatric pulmonology2022

Feasibility of the A-STEP for the assessment of exercise capacity in people with cystic fibrosis.

Lisa M Wilson, Angela Potter, Carol Maher, Matthew J Ellis, Rebecca L Lane, John W Wilson, Dominic T Keating, Shapour Jaberzadeh, Brenda M Button

Abstract read
In one paragraph

Article in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Clinimetric properties of field exercise tests in cystic fibrosis: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lisa M WilsonDepartment of Physiotherapy, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0003-2663-1049
Angela PotterDepartment of Physiotherapy, Women's and Children's Hospital, Adelaide, South Australia, Australia.
Carol MaherDepartment of Allied Health and Human Performance, Alliance for Research in Exercise, Nutrition and Activity (ARENA) Research Centre, University of South Australia, Adelaide, Australia.
Matthew J EllisDepartment of Respiratory Medicine, Alfred Health, Melbourne, Victoria, Australia.
Rebecca L LaneDepartment of Physiotherapy, Victoria University, Melbourne, Victoria, Australia.
John W WilsonDepartment of Respiratory Medicine, Alfred Health, Melbourne, Victoria, Australia.
Dominic T KeatingDepartment of Respiratory Medicine, Alfred Health, Melbourne, Victoria, Australia.
Shapour JaberzadehDepartment of Physiotherapy, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.
Brenda M ButtonDepartment of Physiotherapy, Alfred Health, Melbourne, Victoria, Australia.ORCID 0000-0002-3044-8872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate feasibility of the Alfred Step Test Exercise Protocol (A-STEP) for the assessment of exercise capacity in adults and children with cystic fibrosis (CF); in adults to test whether demographics and/or lung function correlated with exercise capacity.

methodsAdults and children with stable CF from two centres completed the A-STEP (a recently developed incremental maximal-effort step test). Feasibility was evaluated by: usefulness for exercise capacity assessment (measures of exercise capacity were: level reached, exercise-induced desaturation, and achievement of at least one maximal effort criteria); safety; operational factors; time to complete; floor and/or ceiling effects. We used multiple linear regression to test whether demographics and/or lung function correlated with exercise capacity.

resultsA total of 49 participants: 38 adults (18 male), percent predicted (pp) forced expiration in one second (FEV

conclusionIn adults and children with stable CF, the A-STEP was feasible, safe, and operationally easy to use for the assessment of exercise capacity, without floor or ceiling effects. In adults, lung function correlated with exercise capacity.

Indexed as

Cystic FibrosisAdultExercise TestExercise ToleranceFeasibility StudiesHumansMaleRespiratory Function Testsexercise testingincremental testmaximal effortmaximal testoxygen desaturation

Identifiers

PMID35811327
PMCPMC9796135

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.