Evidence map›Paper›PMID 35811323›Full record

ArticleNeurological research and practice2022

COVID-19 outcomes in hospitalized Parkinson's disease patients in two pandemic waves in 2020: a nationwide cross-sectional study from Germany.

Raphael Scherbaum, Dirk Bartig, Daniel Richter, Eun Hae Kwon, Siegfried Muhlack, Ralf Gold, Christos Krogias, Lars Tönges

Open access · diamondAbstract read
In one paragraph

Article in Neurological research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Raphael ScherbaumDepartment of Neurology, St. Josef-Hospital, Ruhr-University Bochum, 44791, Bochum, Germany.
Dirk BartigDRG MARKET, 49069, Osnabrück, Germany.
Daniel RichterDepartment of Neurology, St. Josef-Hospital, Ruhr-University Bochum, 44791, Bochum, Germany.
Eun Hae KwonDepartment of Neurology, St. Josef-Hospital, Ruhr-University Bochum, 44791, Bochum, Germany.
Siegfried MuhlackDepartment of Neurology, St. Josef-Hospital, Ruhr-University Bochum, 44791, Bochum, Germany.
Ralf GoldDepartment of Neurology, St. Josef-Hospital, Ruhr-University Bochum, 44791, Bochum, Germany.
Christos KrogiasDepartment of Neurology, St. Josef-Hospital, Ruhr-University Bochum, 44791, Bochum, Germany.
Lars TöngesDepartment of Neurology, St. Josef-Hospital, Ruhr-University Bochum, 44791, Bochum, Germany. lars.toenges@rub.de.ORCID http://orcid.org/0000-0001-6621-144X
St. Josef-Hospital · DEUniversity Hospitals of the Ruhr-University of Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe individualized clinical and public health management of the COVID-19 pandemic have changed over time, including care of people with PD. The objective was to investigate whether in-hospital COVID-19 outcomes and hospital care utilization of people with PD differed between the first two pandemic waves (W) 2020 in Germany.

methodsWe conducted a nationwide cross-sectional study of inpatients with confirmed COVID-19 and PD between March 1 and May 31 (W1), and October 1 and December 31 (W2), 2020 and 2019, using an administrative database. Outcomes were in-hospital mortality, ICU admission rate, change in hospital care utilization, demographical data, PD clinical characteristics, and selected comorbidities. Differences were assessed between waves, PD/non-PD groups, and years.

resultsWe identified 2600 PD COVID-19 inpatients in W2 who in total showed higher in-hospital mortality rates and lower ICU admission rates, compared to both W1 (n = 775) and W1/W2 non-PD COVID-19 inpatients (n = 144,355). Compared to W1, W2 inpatients were more long-term care-dependent, older, more of female sex, and had less advanced disease. During both waves, PD inpatients were older, more frequently male and long-term care-dependent, and showed more risk comorbidities than non-PD COVID-19 inpatients. Decreases in hospital care utilization were stronger than average for PD inpatients but relatively weaker during W2. Non-COVID-19 PD inpatients showed poorer in-hospital outcomes in 2020 than in 2019 with better outcomes during W2.

conclusionsIn-hospital COVID-19 outcomes and hospital care utilization of PD patients in Germany differed between the two pandemic waves in 2020 with increased in-hospital mortality for PD COVID-19. Overall hospital care utilization for PD was increased during W2.

trial registrationNo trial registration or ethical approval was required because data were publicly available, anonymized, and complied with the German data protection regulations.

Indexed as

COVID-19Health care utilizationIntensive careMortalityParkinson’s disease

Identifiers

PMID35811323
PMCPMC9271552
OpenAlexW4285006725

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.