ArticleJournal of affective disorders2022
Multimorbidity worsened anxiety and depression symptoms during the COVID-19 pandemic in Brazil.
Article in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 12 citations in OpenAlex.
- Impact of the pandemic on sexual function: A comparative study between women of reproductive age and postmenopausal women.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Observational
- The Impact of Psychobiotic Therapy on Anxiety and Depressive Symptoms in Patients with Post-COVID Syndrome-A Randomized, Double-Blind, Placebo-Controlled Trial.Metabolites · 2026Article
- Anxiety-Depressive Disorders in 200 Patients with Post-COVID-19 Syndrome: Prevalence and Predictors from a Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Development and validation of a predictive model for depression risk in older patients with multiple chronic diseases in the community: cross-sectional study based on a health ecology model.Frontiers in public health · 2026Article
- Associations between depression and risk of cardiometabolic multimorbidity among middle-aged and older Chinese adults.Scientific reports · 2025Article
- Depressive symptom trajectories among general population during the COVID-19 pandemic in Iceland: a prospective cohort study (2020-2023).BMJ public health · 2024Article
- Predictors of basic and instrumental activities of daily living among older adults with multiple chronic conditions.BMC geriatrics · 2024Article
- Associations of motor and neuropsychiatric symptoms with comorbidities in prodromal Parkinson's disease.Frontiers in aging neuroscience · 2024Article
- Article
- Relationships between childhood trauma and mental health during the COVID-19 pandemic: a network analysis.Frontiers in psychiatry · 2023Article
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Authors and funding
11 authors at 7 institutions in 5 countries.
Funding
Abstract
Multimorbidity is a global health issue impacting the quality of life of all ages. Multimorbidity with a mental disorder is little studied and is likely to have been affected by the COVID-19 pandemic. We used a survey of 14,007 respondents living in Brazil to investigate whether people who already had at least one chronic medical condition had more depression and anxiety symptoms during social distancing in 2020. Generalized linear models and structural equation modelling were used to estimate the effects. A 19 % and 15 % increase in depressive symptoms were found in females and males, respectively, for each unit of increase in the observed value of reported chronic disease. Older subjects presented fewer symptoms of depression and anxiety. There was a 16 % increase in anxiety symptoms in females for each unit increase in the reported chronic disease variable and a 14 % increase in males. Younger subjects were more affected by anxiety symptoms in a dose-response fashion. High income was significantly related to fewer depressive and anxiety symptoms in both males and females. Physical activity was significantly associated with fewer anxiety and depression symptoms. Structural equation modelling confirmed these results and provided further insight into the hypothesised paths.
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