Evidence map›Paper›PMID 35810600›Full record

Trial reportJournal of psychiatric research2022

Impact of preference for yoga or cognitive behavioral therapy in patients with generalized anxiety disorder on treatment outcomes and engagement.

Kristin L Szuhany, Samrachana Adhikari, Alan Chen, Rebecca E Lubin, Emma Jennings, Madeleine Rassaby, Rachel Eakley, Mackenzie L Brown, Rebecca Suzuki, Abigail L Barthel and 6 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of psychiatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01912287 (GATE), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01912287 nacompletednot on this map

GATE: Generalized Anxiety - A Treatment Evaluation

TypeinterventionalSponsorNYU Langone HealthRan2013 to 2019Enrolled226ConditionsGeneralized Anxiety DisorderArmsCognitive Behavioral Therapy, Stress Education, Yoga
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 3 countries.

Kristin L SzuhanyAnxiety, Stress and Prolonged Grief Program, Department of Psychiatry, New York University Grossman School of Medicine, 1 Park Avenue, 8th Floor, New York, NY, 10016, USA. Electronic address: kristin.szuhany@nyulangone.org.
Samrachana AdhikariDivision of Biostatistics, Department of Population Health, New York University Grossman School of Medicine, 180 Madison Avenue, 4th Floor, New York, NY, 10016, USA. Electronic address: samrachana.adhikari@nyulangone.org.
Alan ChenDivision of Biostatistics, Department of Population Health, New York University Grossman School of Medicine, 180 Madison Avenue, 4th Floor, New York, NY, 10016, USA. Electronic address: alan.chen@nyulangone.org.
Rebecca E LubinDepartment of Psychological & Brain Sciences, Boston University, 900 Commonwealth Ave, 2nd Floor, Boston, MA, 02215, USA. Electronic address: rlubin@bu.edu.
Emma JenningsAnxiety, Stress and Prolonged Grief Program, Department of Psychiatry, New York University Grossman School of Medicine, 1 Park Avenue, 8th Floor, New York, NY, 10016, USA. Electronic address: emma.jennings@nyulangone.org.
Madeleine RassabyAnxiety, Stress and Prolonged Grief Program, Department of Psychiatry, New York University Grossman School of Medicine, 1 Park Avenue, 8th Floor, New York, NY, 10016, USA. Electronic address: madeleine.rassaby@gmail.com.
Rachel EakleyAnxiety, Stress and Prolonged Grief Program, Department of Psychiatry, New York University Grossman School of Medicine, 1 Park Avenue, 8th Floor, New York, NY, 10016, USA. Electronic address: rachel.eakley@nyulangone.org.
Mackenzie L BrownDepartment of Psychological & Brain Sciences, University of Louisville, Life Sciences Building, Louisville, KY, 40292, USA. Electronic address: mlbrow42@louisville.edu.
Rebecca SuzukiDepartment of Psychology, University of Denver, 2155 S. Race St, Denver, CO, 80210, USA. Electronic address: rebecca.suzuki@du.edu.
Abigail L BarthelDepartment of Psychological & Brain Sciences, Boston University, 900 Commonwealth Ave, 2nd Floor, Boston, MA, 02215, USA. Electronic address: abarthel@bu.edu.
David RosenfieldDepartment of Psychology, Southern Methodist University, Expressway Tower 1100N, Dallas, TX, USA. Electronic address: drosenfi@mail.smu.edu.
Susanne S HoeppnerDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Richard B. Simches Research Center, 185 Cambridge St., Suite, 2000, Boston, MA, USA. Electronic address: shoeppner@mgh.harvard.edu.
Sat Bir KhalsaDepartments of Medicine and Neurology, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA, USA. Electronic address: khalsa@hms.harvard.edu.
Eric BuiDepartment of Psychiatry, University of Caen Normandy & Caen University Hospital, Avenue de la Cote de Nacre, Caen, France. Electronic address: bui-th@chu-caen.fr.
Stefan G HofmannDepartment of Psychological & Brain Sciences, Boston University, 900 Commonwealth Ave, 2nd Floor, Boston, MA, 02215, USA; Department of Clinical Psychology, Philipps-University Marburg, Germany, Schulstrasse 12, 35037, Marburg, Germany. Electronic address: shofmann@bu.edu.
Naomi M SimonAnxiety, Stress and Prolonged Grief Program, Department of Psychiatry, New York University Grossman School of Medicine, 1 Park Avenue, 8th Floor, New York, NY, 10016, USA. Electronic address: naomi.simon@nyulangone.org.
New York University · USBoston University · USBrigham and Women's Hospital · USCentre Hospitalier Universitaire de Caen Normandie · FRHarvard University · USSouthern Methodist University · USUniversity of Denver · USUniversity of Louisville · US

Funding

Institutional Career DevelopmentKL2TR001446 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PILLINGER, MICHAEL · 2015 to 2025
$6.7M
1/2-Yoga For Generalized Anxiety DisorderR01AT007257 · NCCIH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI HOFMANN, STEFAN G. · 2013 to 2017
$2.0M
2/2 YOGA FOR GENERALIZED ANXIETY DISORDERR01AT007258 · NCCIH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SIMON, NAOMI M · 2013 to 2017
$1.9M
Optimizing Exercise for the Treatment of AnxietyK23MH122773 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SZUHANY, KRISTIN L. · 2021 to 2025
$887k
NCATS NIH HHS KL2 TR001446NCCIH NIH HHS R01 AT007257NCCIH NIH HHS R01 AT007258NIMH NIH HHS K23 MH122773
6 · The paper itself

Abstract

There is some, but inconsistent, evidence to suggest that matching patient treatment preference enhances treatment engagement and outcome. The current study examined differential preferences and factors associated with treatment preference for 12-week group cognitive behavioral therapy (CBT), yoga, or stress education in 226 adults with generalized anxiety disorder (GAD; 70% female, Mean age = 33 ± 13.5). In a subsample of 165 patients who reported an intervention preference and were randomized to yoga or CBT, we further examined whether match to preferred intervention improved the primary treatment outcome (responder status on Clinical Global Impressions Scale) and engagement (dropout, homework compliance). Preferences for CBT (44%) and yoga (40%) were similar among patients. Women tended to prefer yoga (OR = 2.75, p = .01) and CBT preference was associated with higher baseline perceived stress (OR = 0.92, p = .04) and self-consciousness meta-cognitions (OR = 0.90, p = .02). Among those not matched to their preference, treatment response was higher for those receiving CBT than yoga (OR = 11.73, p = .013); there were no group differences for those matched to their treatment preference. In yoga, those who received their preference were more likely to drop than those who did not (OR = 3.02, 95% CI = [1.20, 7.58], p = .037). This was not the case for CBT (OR = 0.37, 95% CI = [0.13, 1.03], p = .076). Preference match did not predict homework compliance. Overall, results suggest that treatment preference may be important to consider to optimize outcome and engagement; however, it may vary by treatment modality. Future research incorporating preference, especially with yoga for anxiety, is aligned with personalized medicine.

trial registrationclinicaltrials.gov: NCT01912287; https://clinicaltrials.gov/ct2/show/NCT01912287.

Indexed as

Cognitive Behavioral TherapyYogaAdultAnxietyAnxiety DisordersFemaleHumansMaleMiddle AgedTreatment OutcomeYoung AdultCognitive-behavioral therapyEngagementGeneralized anxiety disorderMatchPreferenceYoga

Identifiers

PMID35810600
PMCPMC9969964
OpenAlexW4283808250

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.